Results 61 to 70 of about 360,363 (303)

From DNA sequence to application: possibilities and complications [PDF]

, 1999
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin, A Bruttin, A Kraus, A Nauta, A Nauta, A Nauta, A Sazicu, AK Aggarwal, B Christiansen, B Christiansen, BC Lokman, BC Lokman, BM Chassy, C Delorme, C Hill, C Schouler, CA Alpert, CA Shearman, CJ Hueck, CO Pabo, CT Verrips, D Botstein, D Lillehaug, D Lillehaug, D Sinderen, DJ O’Sullivan, DJ O’Sullivan, DO Gostick, DO Gostick, E Küster, E Maguin, E Stanley, EJ Luesink, EJ Luesink, EJ Luesink, F Desiere, F Desiere, G Buist, G Buist, G Ramsay, G Vriend, GM Djordjevic, GM Djordjevic, H Brüssow, H Holo, H Neve, I Biswas, J Bardowski, J Bernhardt, J Green, J Law, J Payne, J Stülke, JB Luchansky, JD Boyce, JW Sanders, JW Sanders, JW Sanders, K Chung, K Leenhouts, K Leenhouts, K Leenhouts, K Schnetz, KI Kodaira, KJ Leenhouts, L Dupont, L Dupont, LJ Beamer, LR Garcia, M Curie, M de Guchte, M de Guchte, M Lieb, M Ptashne, MG Johnsen, MJ Gasson, MJ Weickert, MM Sheehan, MW Lubbers, MW Lubbers, N Goupil-Feuillerat, OP Kuipers, P Hals, PG Ruyter, PGGA Ruyter, PL Madsen, PS Chandry, R Parreira, R Schmid, R Young, R Young, RR Raya, S Challou, S Lucchini, S Lucchini, S Simonen, S Spiro, S Spiro, SA Walker, SB Mclvilc, SG Kim, SM Heller, SM Madsen, SR Swindell, T Sasaki, TM Ramseier, V Vagner, WM Vos, WM Vos, WM Vos, Y Fujita   +110 more
core   +3 more sources

Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis

Plants, 2013
We produced transgenic Arabidopsis plants that express chimeric genes for transcription factors converted to dominant repressors, using Chimeric REpressor gene-Silencing Technology (CRES-T), and evaluated the salt tolerance of each line.
Daisuke Kazama, Masateru Itakura, Takamitsu Kurusu, Nobutaka Mitsuda, Masaru Ohme-Takagi, Yuichi Tada   +5 more
doaj   +1 more source

Interplay of protein and DNA structure revealed in simulations of the lac operon. [PDF]

PLoS ONE, 2013
The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop.
Luke Czapla, Michael A Grosner, David Swigon, Wilma K Olson   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Estudos Sôbre Regulação Metabólica Contrôle de Síntese de Proteínas: V - Ação da Glicose na Regulação da Tirosina Alfa Ceto Glutarato Transaminase em Fígado de Rato

Revista Brasileira de Cancerologia, 2023
O presente trabalho demonstra que o efeito “repressor” da glicose sôbre TT no fígado não se apresenta se o animal fôr previamente tratado com 5-PU. Porém, o 5-FU não evita o efeito da glicose, se fôr administrado depois dêste glicidio.
Mauro C. Faria, F. G. Mello, P. Preza, H. C. Faria   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Diffusive hidden Markov model characterization of DNA looping dynamics in tethered particle experiments [PDF]

, 2007
In many biochemical processes, proteins bound to DNA at distant sites are brought into close proximity by loops in the underlying DNA. For example, the function of some gene-regulatory proteins depends on such DNA looping interactions.
Andrec M, Bevington P R, Colquhoun D, Cox D R, Gelles J, John F Beausang, Philip C Nelson, Press W H, Qian H, Qin F, Qin F, Smith D A, Wong O K Guthold M Erie D A Gelles J, Yin H, Zocchi G, Zurla C   +15 more
core   +3 more sources

The N-terminal domain of the repressor of Staphylococcus aureus phage Φ11 possesses an unusual dimerization ability and DNA binding affinity. [PDF]

PLoS ONE, 2014
Bacteriophage Φ11 uses Staphylococcus aureus as its host and, like lambdoid phages, harbors three homologous operators in between its two divergently oriented repressor genes. None of the repressors of Φ11, however, showed binding to all three operators,
Anindya Biswas, Sukhendu Mandal, Subrata Sau   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nonlinear software sensor for monitoring genetic regulation processes with noise and modeling errors

, 2004
Nonlinear control techniques by means of a software sensor that are commonly used in chemical engineering could be also applied to genetic regulation processes.
B. C. Goodwin, B. Lewin, D. J. Lockhart, D. L. Nelson, G. Argüello, G. Stephanopoulos, H. C. Rosu, H. Shim, J. Collado-Vides, J. J. Tyson, J. P. Gauthier, L. A. Torres, P. S. Swain, R. Hermann, U. Alon, V. Ibarra-Junquera, W. A. Wolovich   +16 more
core   +1 more source