Results 191 to 200 of about 6,797,208 (350)
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins
Proceedings of the National Academy of Sciences of the United States of America, 2002 semanticscholar +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Transcriptional regulatory repressor protein EthR (Rv3855) [PDF]
Science-Business eXchange, 2008 openaire +1 more source
Cro Repressor Protein and Its Interaction with DNA
Cold Spring Harbor Symposia on Quantitative Biology, 1983 B W, Matthews +4 more
openaire +2 more sources
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, EarlyView.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Molecular Mechanisms of Transcription Factors with Dual Activator and Repressor Functions. [PDF]
Mol Cell BiolDong J, Guertin MJ.
europepmc +1 more source
Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins. [PDF]
Sci Rep, 2016 Shi M +6 more
europepmc +1 more source
Advanced Science, EarlyView.This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi +11 more
wiley +1 more source