Results 91 to 100 of about 739,587 (347)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Biology, economy and reproduction [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 2007 Economic theories have been used to explain fertility patterns 1, 2. Reduced fertility in the Western world has been explained by changes in women's investment from child bearing to education and p...
openaire +2 more sources
Reproductive biology and length-weight relationship of the Pool Barb Puntius sophore (Hamilton, 1832) in Mymensingh, Bangladesh [PDF]
, 2023 Md. Rabiul Awal +4 more
openalex +1 more source
USSR Space Life Sciences Digest, issue 29 [PDF]
This is the twenty-ninth issue of NASA's Space Life Sciences Digest. It is a double issue covering two issues of the Soviet Space Biology and Aerospace Medicine Journal.
Rowe, Joseph +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Spatial transcriptomics identifies candidate stromal drivers of benign prostatic hyperplasia
JCI InsightBenign prostatic hyperplasia (BPH) is the nodular proliferation of the prostate transition zone in older men, leading to urinary storage and voiding problems that can be recalcitrant to therapy.
Anna S. Pollack +9 more
doaj +1 more source
Apoptosis in reproductive biology [PDF]
Cell Death & Differentiation, 1997 Recent studies aimed at a greater understanding of the occurrence and regulation of cell death in reproductive biology provide a promising new direction for novel approaches to understanding normal and pathological aspects of reproduction. Several instances of physiologically occurring cell death (programmed cell death, PCD), associated with ...
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Protein disulfide isomerase is essential for spermatogenesis in mice
JCI InsightSpermatogenesis requires precise posttranslational control in the endoplasmic reticulum (ER), but the mechanism remains largely unknown. The protein disulfide isomerase (PDI) family is a group of thiol oxidoreductases responsible for catalyzing the ...
Yaqiong Zhang +7 more
doaj +1 more source