Results 91 to 100 of about 870,336 (295)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Examining the Unregulated Use of Hormonal Preparations in Animal Reproduction
Hormones play a pivotal role in addressing diverse reproductive disorders in domestic animals, with their prevalence surpassing antibiotics in daily veterinary practice.
Akhter Rasool +3 more
doaj +1 more source
Cross-sectional analysis of sleep hours and quality with sex hormones in men
Background: Reduced total hours of sleep and low quality of sleep have been suggested to be associated with low levels of male hormones. Few studies have examined the association between excessive sleep and male reproductive hormones.
Morten Ruge +3 more
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Effective Use of Reproductive Hormones in Breeding Programs
Wiltbank, Milo C.. (2001). Effective Use of Reproductive Hormones in Breeding Programs.
Wiltbank, Milo C.
core
Sex steroid hormones and reproductive disorders: impact on women's health
The role of sex steroid hormones in reproductive function in women is well established. However, in the last two decades it has been shown that receptors for estrogens, progesterone and androgens are expressed in non reproductive tissue /organs (bone ...
Moley, KH +84 more
core +1 more source
The present study marks a significant step forward in validating the use of skin biopsies for measuring reproductive steroid hormones in sharks. Given the conservation concerns surrounding many chondrichthyan species and the growing emphasis on adhering ...
Annaïs Carbajal +5 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
REPRODUCTIVE HORMONES AND CORTISOL RESPONSES TO PLYOMETRIC TRAINING IN MALES
Plyometric training activities are commonly used by a wide range of athletes to increase jump performance and improve explosive power and muscular activation patterns.
Serife Vatansever Ozen
core

