Results 101 to 110 of about 219,005 (309)

Exploring the anthelmintic properties of Australian native shrubs with respect to their potential role in livestock grazing systems [PDF]

, 2009
We measured in vitro anthelmintic activity in extracts from 85 species of Australian native shrub, with a view to identifying species able to provide a degree of worm control in grazing systems.
A. C. KOTZE, A. F. TOOVEY, Barry, Barry, D. K. REVELL, Dynes, Edwards, Howard, Hubert, J. EMMS, J. O'GRADY, M. BENNELL, Maniatis, Mathams, P. E. VERCOE, P. JESSOP, Revell, S. HUGHES   +17 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Screening and Mechanism Study of Three Antagonistic Drugs, Oxysophoridine, Rutin, and Phellodendrine, against Zearalenone-Induced Reproductive Toxicity in Ovine Oocytes

Antioxidants
Zearalenone (ZEN) is a common fungal toxin with reproductive toxicity in various grains. It poses a serious threat to ovine and other animal husbandry industries, as well as human reproductive health.
Zongshuai Li, Tian Ma, Yali Liu, Wanruo Liu, Xingxu Zhao, Gaiping Zhang, Jianlin Wang, Yong Zhang   +7 more
doaj   +1 more source

Development and standardization of a protocol for sperm cryopreservation of two important commercial oyster species [PDF]

, 2015
Dissertação de mestrado, Aquacultura e Pescas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2015Aquaculture activities have a huge contribution for the world food production and their development is extremely necessary to answer to the ...
Melo, Francisca Félix de Azeredo Pinto e
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Reproductive and developmental implications of micro- and nanoplastic internalization: Recent advances and perspectives

Ecotoxicology and Environmental Safety
A growing body of evidence exhibits the ubiquitous presence and accumulation of micro- and nanoplastics (MNPs) in the air, drinking water, food, and even inside the body, which has raised concerns about their potential impact on reproductive and ...
Zitong Zhang, Jiahua Meng, Jiaqi Tian, Ning Li, Zhen Chen, Xiang Yun, Dandan Song, Fei Li, Shuyin Duan, Lin Zhang   +9 more
doaj   +1 more source

Bisphenol A induces superfeminization in the Ramshorn snail Marisa cornuarietis (Gastropoda: Prosobranchia) at environmentally relevant concentrations [PDF]

, 2007
Previous investigations have shown that bisphenol A (BPA) induces a superfeminization syndrome in the freshwater snail Marisa cornuarietis at concentrations as low as 1 μg/L.
Bachmann, Jean, Kloas, Werner, Lutz, Ilka, Oehlmann, Jörg, Oetken, Matthias, Schulte-Oehlmann, Ulrike, Ternes, Thomas A.   +6 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The accumulation of Microcystin-LR in the gonads of Pelophylax nigromaculatus during the reproductive periods induces reproductive endocrine disorders in their offspring

Ecotoxicology and Environmental Safety
Microcystin-LR’s reproductive (reproductive and non-reproductive periods) and transgenerational toxicity in amphibians remains poorly understood. Adult Pelophylax nigromaculatus in reproductive and non-reproductive periods were exposed to MC-LR to ...
Huijuan Zhang, Yuefei Ruan, Zifang Ding, Zheng Li, Jun He, Jing Li, Pei Hong, Hailong Wu, Yilin Shu   +8 more
doaj   +1 more source

Acute toxicity of synyhetic resin effluent to African Catfish, Clarias gariepinus [BURCHELL, 1822]. [PDF]

, 2012
Aquatic pollution as a field has gained a lot of attention over the decades majorly because of the vital role the aquatic environment plays in the human lifecycle.
Dahunsi, S. O., Oranusi, S. U.
core   +1 more source