Results 71 to 80 of about 223,319 (331)

Biological Magnification of Microplastics: A Look at the Induced Reproductive Toxicity from Simple Invertebrates to Complex Vertebrates [PDF]

, 2023
Muhammad Bilal, Habib Ul Hassan, Madiha Taj, Naseem Rafiq, Ghulam Nabi, Asif Ali, Karim Gabol, Muhammad Ishaq Ali Shah, Rizwana Abdul Ghaffar, Muhammad Sohail, Takaomi Arai   +10 more
openalex   +1 more source

A screening method for ranking chemicals by their fate and behaviour in the environment and potential toxic effects in humans following non-occupational exposure [PDF]

, 2004
A large number of chemicals are released intentionally or unintentionally into the environment each year. These include thousands of substances that are currently listed worldwide and several hundred new substances added annually (Mücke et al., 1986 ...
Capelton, A, Duarte-Davidson, R, Troisi, G   +2 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Behavioral Studies of Zebrafish Reveal a New Perspective on the Reproductive Toxicity of Micro- and Nanoplastics

Toxics
The escalating prevalence of microplastics and nanoplastics in aquatic environments is a major challenge affecting the behavior and reproductive health of aquatic organisms while posing potential risks to human health and ecosystems.
Baihui Wu, Haiyang Yu, Jia Yi, Pengyu Lei, Jiaxuan He, Jing Ruan, Peiye Xu, Runchao Tao, Libo Jin, Wei Wu, Qinsi Yang, Da Sun, Xiaoqun Zhang   +12 more
doaj   +1 more source

Safety profile of 40% Garcinol from Garcinia indica in experimental rodents

Toxicology Reports, 2018
The present study was taken up to evaluate the single dose acute toxicity, 28 days and 90 days repeated dose toxicity and reproductive/developmental toxicity of standardized 40% Garcinol in experimental rodents.
Muhammed Majeed, Sarang Bani, Beena Bhat, Anjali Pandey, Lakshmi Mundkur, Prakriti Neupane   +5 more
doaj   +1 more source

Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review

Particle and Fibre Toxicology, 2023
Background Adverse outcome pathways (AOPs) are conceptual frameworks that organize knowledge about biological interactions and toxicity mechanisms. They present a sequence of events commencing with initial interaction(s) of a stressor, which defines the ...
Ozge Kose, Paride Mantecca, Anna Costa, Marie Carrière   +3 more
doaj   +1 more source

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. [PDF]

, 2020
Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones.
Biglia, Nicoletta, Birkhaeuser, Martin, Brincat, Mark, Celis-Gonzales, Cuauhtémoc, Depypere, Herman, Egarter, Christian, Fait, Tomas, Genazzani, Andrea, Goldstein, Steven, Mueck, Alfred, Palacios, Santiago, Panay, Nick, Ruan, Xiangyan, Simoncini, Tommaso, Skouby, Sven O   +14 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Studies on the toxicity of Vacor (RH-787) on the reproductive biology of Rattus rattus rufescens [PDF]

, 1980
Vacor (RH-787), a relatively new rodenticide, was evaluated for the control of Rattus rattus rufescens. The symptoms of paralysis in hind limbs were observed after feeding it to rodents.
Saxena, Y., Sharma, P. P., Zutshi, M.
core  

The surface reactivity of iron oxide nanoparticles as a potential hazard for aquatic environments: A study on Daphnia magna adults and embryos [PDF]

, 2018
open5noNano-ecotoxicology is extensively debated and nanomaterial surface reactivity is an emerging topic. Iron oxide nanoparticles are widely applied, with organic or inorganic coatings for stabilizing their suspensions.

core   +1 more source