Results 121 to 130 of about 403,028 (282)

YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8^+ T cells

Nature Immunology, 2023
Shoubao Ma, Baofa Sun, Songqi Duan, Jingjing Han, Tasha Barr, Jianying Zhang, M. Bissonnette, M. Kortylewski, Chuan He, Jianjun Chen, M. Caligiuri, Jianhua Yu   +11 more
semanticscholar   +1 more source

Viral reprogramming [PDF]

Nature Reviews Cancer, 2018
Two studies have shown that oncolytic virus treatment prior to surgery can prime the tumour immune microenvironment for subsequent immune checkpoint inhibition and lead to better outcomes in preclinical models of breast and brain cancers.
openaire   +3 more sources

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

Cell Research, 2015
Activation of macrophages and dendritic cells (DCs) by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from oxidative phosphorylation (OXPHOS), similar to the Warburg effect in tumors.
B. Kelly, L. O’Neill
semanticscholar   +1 more source

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease

Advanced Science
Direct lineage reprogramming into dopaminergic (DA) neurons holds great promise for the more effective production of DA neurons, offering potential therapeutic benefits for conditions such as Parkinson's disease.
Byounggook Cho, Junyeop Kim, Sumin Kim, Saemin An, Yerim Hwang, Yunkyung Kim, Daeyeol Kwon, Jongpil Kim   +7 more
doaj   +1 more source

Reprogramming, in Print and in Person [PDF]

Cell Stem Cell, 2011
In honor of the Cell Symposia series conference on Stem Cell Programming and Reprogramming taking place in Lisbon on December 8–10, this month's issue contains a special focus on reprogramming. Our Review and Perspective articles both come from speakers at the meeting.
openaire   +3 more sources

Inhibition of Polo-like Kinase 1 Prevents the Male Pronuclear Formation Via Alpha-tubulin Recruiting in In Vivo-fertilized Murine Embryos

Journal of Animal Reproduction and Biotechnology, 2018
Polo-like kinase 1 (Plk1) has been known to be a critical element in cell division including centrosome maturation, cytokinesis and spindle formation in somatic, cancer, and mammalian embryonic cells.
Jeonghyeon Moon, Sangho Roh
doaj   +1 more source

Partial restriction of genome expression — a component of its work reprogramming in regenerating liver of mammals [PDF]

, 1989
M. Yu. Obolenskaya, Victor Prima, Tsvetelina Gerasimova, O. M. Platonov   +3 more
openalex   +1 more source

Transcriptome Analyses in Adult Olive Trees Indicate Acetaldehyde Release and Cyanide-Mediated Respiration Traits as Critical for Tolerance against Xylella fastidiosa and Suggest AOX Gene Family as Marker for Multiple-Resilience

Pathogens
Xylella fastidiosa (Xf) is a global bacterial threat for a diversity of plants, including olive trees. However, current understanding of host responses upon Xf-infection is limited to allow early disease prediction, diagnosis, and sustainable strategies ...
Birgit Arnholdt-Schmitt, Debabrata Sircar, Shahid Aziz, Thais Andrade Germano, Karine Leitão Lima Thiers, Carlos Noceda, Revuru Bharadwaj, Gunasekaran Mohanapriya, José Hélio Costa   +8 more
doaj   +1 more source

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]

, 2017
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen, Malvin, Nicole P, Miyoshi, Hiroyuki, Ryu, Stacy H, Sonnek, Naomi M, Stappenbeck, Thaddeus S, VanDussen, Kelli L, Wang, Yi   +7 more
core   +2 more sources