Results 121 to 130 of about 175,723 (295)

Author Correction: Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells

open access: yesScientific Reports, 2023
Zhicong Chen   +11 more
doaj   +1 more source

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back   +3 more
wiley   +1 more source

Harmful or Not: Trichostatin A treatment of embryos generated by ICSI or ROSI

open access: yesOpen Life Sciences, 2006
Kishigami Satoshi   +8 more
doaj   +1 more source

Efficient Rebalancing of ROS Levels in Plants Links to Temporarily Enhanced Aerobic Fermentation, Distinct Cell Restructuration, and Resilience in Field [PDF]

open access: yesInnovations in Digital Health, Diagnostics, and Biomarkers, 2022
Birgit Arnholdt-Schmitt   +2 more
doaj   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua   +9 more
wiley   +1 more source

Engineering extracellular vesicles for ROS scavenging and tissue regeneration

open access: yesNano Convergence
Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist. Emerging as a safer and potentially more effective alternative, extracellular vesicles (EVs) derived from stem cells exhibit remarkable abilities to activate ...
Ahmed Abdal Dayem   +6 more
doaj   +1 more source

An erythromycin analog produced by reprogramming of polyketide synthesis.

open access: green, 1993
Stefano Donadio   +4 more
openalex   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

Transcriptional reprogramming of dendritic cells by differentiation stimuli [PDF]

open access: bronze, 2001
Francesca Granucci   +4 more
openalex   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

open access: yesAdvanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu   +16 more
wiley   +1 more source

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