Results 11 to 20 of about 403,028 (282)

An Algorithm for Cellular Reprogramming [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
The day we understand the time evolution of subcellular elements at a level of detail comparable to physical systems governed by Newton's laws of motion seems far away.
Bloch, Anthony   +7 more
core   +4 more sources

Time-LLM: Time Series Forecasting by Reprogramming Large Language Models [PDF]

open access: yesInternational Conference on Learning Representations, 2023
Time series forecasting holds significant importance in many real-world dynamic systems and has been extensively studied. Unlike natural language process (NLP) and computer vision (CV), where a single large model can tackle multiple tasks, models for ...
Ming Jin   +10 more
semanticscholar   +1 more source

WARP: Word-level Adversarial ReProgramming [PDF]

open access: yesAnnual Meeting of the Association for Computational Linguistics, 2021
Transfer learning from pretrained language models recently became the dominant approach for solving many NLP tasks. A common approach to transfer learning for multiple tasks that maximize parameter sharing trains one or more task-specific layers on top ...
Karen Hambardzumyan   +2 more
semanticscholar   +1 more source

Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

open access: yesJournal of Hematology & Oncology, 2023
Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain uncontrolled proliferation and survive in unfavorable environments that lack oxygen and nutrients, tumor cells undergo metabolic transformations to exploit various ways ...
Haoran Jin   +6 more
semanticscholar   +1 more source

"Nuclear Reprogramming" and "Epigenetic Reprogramming"

open access: bronzeJournal of Mammalian Ova Research, 2004
Takashi Tada   +2 more
openalex   +4 more sources

Macrophage reprogramming for therapy [PDF]

open access: yesImmunology, 2021
SummaryDysfunction of the immune system underlies a plethora of human diseases, requiring the development of immunomodulatory therapeutic intervention. To date, most strategies employed have been focusing on the modification of T lymphocytes, and although remarkable improvement has been obtained, results often fall short of the intended outcome. Recent
Natacha Ipseiz   +4 more
openaire   +3 more sources

Metabolic reprogramming in cancer: Mechanisms and therapeutics

open access: yesMedComm, 2023
Cancer cells characterized by uncontrolled growth and proliferation require altered metabolic processes to maintain this characteristic. Metabolic reprogramming is a process mediated by various factors, including oncogenes, tumor suppressor genes ...
Shiqi Nong   +9 more
semanticscholar   +1 more source

Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

open access: yesExperimental and Molecular Medicine, 2023
Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In cancer cells, metabolic pathway activity varies during tumorigenesis and cancer progression, indicating regulated metabolic plasticity.
Xuemeng Xu   +16 more
semanticscholar   +1 more source

Menin orchestrates hepatic glucose and fatty acid uptake via deploying the cellular translocation of SIRT1 and PPARγ

open access: yesCell & Bioscience, 2023
Background Menin is a scaffold protein encoded by the Men1 gene, which interacts with various transcriptional proteins to activate or repress cellular processes and is a key mediator in multiple organs.
Tingjun Liu   +7 more
doaj   +1 more source

The role of lipid metabolic reprogramming in tumor microenvironment

open access: yesTheranostics, 2023
Metabolic reprogramming is one of the most important hallmarks of malignant tumors. Specifically, lipid metabolic reprogramming has marked impacts on cancer progression and therapeutic response by remodeling the tumor microenvironment (TME).
Kai Yang   +9 more
semanticscholar   +1 more source

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