Results 11 to 20 of about 376,055 (402)

Model Reprogramming: Resource-Efficient Cross-Domain Machine Learning [PDF]

arXiv, 2022
In data-rich domains such as vision, language, and speech, deep learning prevails to deliver high-performance task-specific models and can even learn general task-agnostic representations for efficient finetuning to downstream tasks. However, deep learning in resource-limited domains still faces multiple challenges including (i) limited data, (ii ...
Pin-Yu Chen
arxiv   +3 more sources

Time-LLM: Time Series Forecasting by Reprogramming Large Language Models [PDF]

International Conference on Learning Representations, 2023
Time series forecasting holds significant importance in many real-world dynamic systems and has been extensively studied. Unlike natural language process (NLP) and computer vision (CV), where a single large model can tackle multiple tasks, models for ...
Ming Jin, Shiyu Wang, Lintao Ma, Zhixuan Chu, James Y. Zhang, X. Shi, Pin-Yu Chen, Yuxuan Liang, Yuan-Fang Li, Shirui Pan, Qingsong Wen   +10 more
semanticscholar   +1 more source

WARP: Word-level Adversarial ReProgramming [PDF]

Annual Meeting of the Association for Computational Linguistics, 2021
Transfer learning from pretrained language models recently became the dominant approach for solving many NLP tasks. A common approach to transfer learning for multiple tasks that maximize parameter sharing trains one or more task-specific layers on top ...
Karen Hambardzumyan, Hrant Khachatrian, Jonathan May   +2 more
semanticscholar   +1 more source

Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

Journal of Hematology & Oncology, 2023
Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain uncontrolled proliferation and survive in unfavorable environments that lack oxygen and nutrients, tumor cells undergo metabolic transformations to exploit various ways ...
Haoran Jin, Jin Wang, Zi-Jing Wang, Mingjia Xi, Bi-Han Xia, Kai Deng, Jin-Lin Yang   +6 more
semanticscholar   +1 more source

Metabolic reprogramming in cancer: Mechanisms and therapeutics

MedComm, 2023
Cancer cells characterized by uncontrolled growth and proliferation require altered metabolic processes to maintain this characteristic. Metabolic reprogramming is a process mediated by various factors, including oncogenes, tumor suppressor genes ...
Shiqi Nong, Xiaoyue Han, Yu Xiang, Yu Qian, Yuhao Wei, Tingyue Zhang, Keyue Tian, K. Shen, Jing Yang, Xuelei Ma   +9 more
semanticscholar   +1 more source

The role of lipid metabolic reprogramming in tumor microenvironment

Theranostics, 2023
Metabolic reprogramming is one of the most important hallmarks of malignant tumors. Specifically, lipid metabolic reprogramming has marked impacts on cancer progression and therapeutic response by remodeling the tumor microenvironment (TME).
Kai Yang, Xiaokun Wang, C. Song, Zhao He, Ruixin Wang, Yongrui Xu, Guanyu Jiang, Yuan Wan, Jie Mei, Wenjun Mao   +9 more
semanticscholar   +1 more source

The cancer metabolic reprogramming and immune response

Molecular Cancer, 2021
The overlapping metabolic reprogramming of cancer and immune cells is a putative determinant of the antitumor immune response in cancer. Increased evidence suggests that cancer metabolism not only plays a crucial role in cancer signaling for sustaining ...
Longzheng Xia, Linda Oyang, Jinguan Lin, Shiming Tan, Yaqian Han, Nayiyuan Wu, Pin Yi, Lu Tang, Qing Pan, Shan Rao, Jiaxin Liang, Yanyan Tang, Min Su, Xia Luo, Yiqing Yang, Ying-rui Shi, Hui Wang, Yujuan Zhou, Q. Liao   +18 more
semanticscholar   +1 more source

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

Nature, 2023
A new reprogramming strategy used to produce human induced pluripotent stem cells from somatic cells results in epigenetic and functional profiles that are highly similar to those of human embryonic stem cells.
S. Buckberry, Xiaodong Liu, Daniel Poppe, J. Tan, Gui-zhi Sun, Joseph Chen, Trung Nguyen, Alex de Mendoza, Jahnvi Pflueger, Thomas Frazer, Dulce B. Vargas-Landín, Jacob M. Paynter, Nathan Smits, N. Liu, John F. Ouyang, F. Rossello, Hun S. Chy, O. Rackham, A. Laslett, J. Breen, G. Faulkner, C. Nefzger, J. Polo, R. Lister   +23 more
semanticscholar   +1 more source

Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview

Frontiers in Cell and Developmental Biology, 2023
The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is widely expressed in the central and peripheral nervous systems. This receptor is implicated in both brain development and adult neurogenesis thanks to its ability to mediate ...
Angela Maria Giada Giovenale, Angela Maria Giada Giovenale, Giorgia Ruotolo, Giorgia Ruotolo, Amata Amy Soriano, Elisa Maria Turco, Giovannina Rotundo, Alessia Casamassa, Angela D’Anzi, Angelo Luigi Vescovi, Angelo Luigi Vescovi, Jessica Rosati   +11 more
doaj   +1 more source

Metabolic reprogramming and epigenetic modifications on the path to cancer

Protein & Cell, 2021
Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally regulate each other, are among the well-known cancer hallmarks. Recent evidence suggests that many metabolites serve as substrates or cofactors of chromatin-modifying
Linchong Sun, Huafeng Zhang, P. Gao
semanticscholar   +1 more source