Results 21 to 30 of about 358,538 (335)
Fission for reprogramming [PDF]
Cell Cycle, 2016 The OSKM (Oct3/4, Sox2, Klf4, and c-Myc) factors trigger a complex array of signals that promote the reprogramming of somatic cells.
Juan Pablo Muñoz, Antonio Zorzano
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A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]
, 2018 open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...
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Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation [PDF]
, 2018 Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal recessive RP. The human iPS cell line, CABi002-A, derived from peripheral blood mononuclear cells from a patient carrying a ...
Bhattacharya, Shomi S. +5 more
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Induced neuronal reprogramming [PDF]
Journal of Comparative Neurology, 2014 ABSTRACTCellular differentiation processes during normal embryonic development are guided by extracellular soluble factors such as morphogen gradients and cell contact signals, eventually resulting in induction of specific combinations of lineage‐determining transcription factors.
Cheen Euong, Ang, Marius, Wernig
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Flexible Sensor Network Reprogramming for Logistics [PDF]
, 2007 Besides the currently realized applications, Wireless Sensor Networks can be put to use in logistics processes. However, doing so requires a level of flexibility and safety not provided by the current WSN software platforms.
Evers, L., Havinga, P.J.M., Kuper, J.
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miRNA-based rapid differentiation of purified neurons from hPSCs advancestowards quick screening for neuronal disease phenotypes in vitro [PDF]
, 2020 Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases in vitro using human pluripotent stem cells (hPSCs).
Aoyama, Takeshi +10 more
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Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]
, 2017 Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J +15 more
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Bmi1 puSHHes reprogramming [PDF]
Cell Research, 2011 In 2006, the group of Shinya Yamanaka demonstrated that somatic cells could be reprogrammed into induced pluripotent stem cells (iPSCs) by ectopic expression of four transcription factors associated to stemness: Oct4, Sox2, Klf4 and c-Myc 1. This groundbreaking discovery opened the possibility of generating patient-specific cells for research, drug ...
Han Li, Manuel Serrano
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Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
, 2017 In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
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Multiplexed promoterless gene expression with CRISPReader
Genome Biology, 2019 Background Genes are comprised of DNA codes and contain promoters and other control elements for reading these codes. The rapid development of clustered regularly interspaced short palindromic repeats (CRISPR) technology has made possible the ...
Hengji Zhan +5 more
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