Results 31 to 40 of about 169,054 (174)
Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy
Neoplasia: An International Journal for Oncology Research, 2013 Gene transfer of drug resistance (CTX-R) genes can be used to protect the hematopoietic system from the toxicity of anticancer chemotherapy and this concept recently has been proven by overexpression of a mutant O6-methylguaninemethyltransferase in the ...
Nico Lachmann +5 more
doaj +1 more source
Improved Input Reprogramming for GAN Conditioning [PDF]
arXiv, 2022 We study the GAN conditioning problem, whose goal is to convert a pretrained unconditional GAN into a conditional GAN using labeled data. We first identify and analyze three approaches to this problem -- conditional GAN training from scratch, fine-tuning, and input reprogramming. Our analysis reveals that when the amount of labeled data is small, input
arxiv
Lost in translation: pluripotent stem cell‐derived hematopoiesis
EMBO Molecular Medicine, 2015 Pluripotent stem cells (PSCs) such as embryonic stem cells or induced pluripotent stem cells represent a promising cell type to gain novel insights into human biology.
Mania Ackermann +3 more
doaj +1 more source
Frontiers in Physiology, 2017 The growth arrest-specific transcript 5 (GAS5) is a long noncoding RNA with low expression in multiple cancers. This meta-analysis aims to explore the association between GAS5 expression levels and cancer patients' prognosis.
Qunjun Gao +8 more
doaj +1 more source
Music Instrument Classification Reprogrammed [PDF]
arXiv, 2022 The performance of approaches to Music Instrument Classification, a popular task in Music Information Retrieval, is often impacted and limited by the lack of availability of annotated data for training. We propose to address this issue with "reprogramming," a technique that utilizes pre-trained deep and complex neural networks originally targeting a ...
arxiv
Nature Communications, 2019 WDFY2 is known as a tumour suppressor but its function is unclear. Here, the authors show that WDFY2 interacts with the v-SNARE VAMP3, leading to a suppression of the metalloprotease MT1-MMP secretion, suggesting that WDFY2 acts a tumour suppressor by ...
Marte Sneeggen +5 more
doaj +1 more source
Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration
Cells, 2020 Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding and characterizing the biochemical context of the cardiovascular system in health and disease is a necessary preliminary step for developing novel therapeutic ...
Aaron H. Wasserman +2 more
doaj +1 more source
Molecules, 2021 Salivary gland stem cells (SGSCs) are potential cell sources for the treatment of salivary gland diseases. The control of cell survival is an essential factor for applying stem cells to regenerative medicine or stem cell-based research.
Kichul Kim +4 more
doaj +1 more source
Journal of Animal Reproduction and Biotechnology, 2018 Hedgehog (Hh) pathway plays a key role in development from invertebrate to vertebrate. It is known to be involved in cell differentiation, polarity, proliferation, including the development of vertebrate limb and the establishment of flies’ body plan. To
Jaehyun Park +4 more
doaj +1 more source
Molecular Biomedicine, 2022 Cancer metastasis is the primary cause of the high mortality rate among human cancers. Efforts to identify therapeutic agents targeting cancer metastasis frequently fail to demonstrate efficacy in clinical trials despite strong preclinical evidence ...
Jerry Xiao +11 more
doaj +1 more source