Results 71 to 80 of about 403,028 (282)
Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]
, 2019 York University ...
Bhattacharya, Debasmita, Scimè, Anthony
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LncRNA‐mediated posttranslational modifications and reprogramming of energy metabolism in cancer
Cancer Communications, 2020 Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism has historically been considered a general phenomenon of tumors. It is well recognized that long noncoding RNAs (lncRNAs) regulate energy metabolism in cancer. However,
Yue Tan +5 more
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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals
Genome Biology, 2021 Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon +13 more
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Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]
, 2016 Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P +9 more
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Nucleic Acids ResearchThe process of induced pluripotent stem cells (iPSCs) reprogramming involves several crucial events, including the mesenchymal-epithelial transition (MET), activation of pluripotent genes, metabolic reprogramming, and epigenetic rewiring.
Xinglin Hu +9 more
semanticscholar +1 more source
A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]
, 2018 open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...
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Trained Immunity: Reprogramming Innate Immunity in Health and Disease.
Annual Review of Immunology, 2021 Traditionally, the innate and adaptive immune systems are differentiated by their specificity and memory capacity. In recent years, however, this paradigm has shifted: Cells of the innate immune system appear to be able to gain memory characteristics ...
S. Bekkering +4 more
semanticscholar +1 more source
Scientific Reports, 2016 TINCR is a well-known lncRNA which acts as a master regulator in somatic differentiation development. However, it is still unclear whether TINCR is also involved in caner occurrence and progression.
Zhicong Chen +11 more
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Molecules, 2020 Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park +5 more
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Reprogramming the Genetic Code [PDF]
Science, 2011 Incorporating unnatural amino acids into proteins presents challenges in expanding the genetic code.
openaire +3 more sources