Results 111 to 120 of about 10,605,669 (311)
Urban ScienceUrban public space faces increasing challenges due to the accelerating impacts of climate change, necessitating a paradigm shift in how cities adapt their built environments.
Juan Sádaba +2 more
doaj +1 more source
Designing online delivery through educational design research
ASCILITE Publications, 2018 This paper reports on an early-stage educational design research project to develop scalable online delivery at a higher education institution with relatively low maturity with digital learning. This involves not only an intervention aimed at transforming the curriculum and teaching practices, but also considers the broader set of institutional ...
openaire +1 more source
Translating material and design space:Strategies to design with curved creased surfaces [PDF]
, 2009 This paper shares findings from the project DevA (Developable surfaces in Architecture), a research by design based project developed a collaboration between academic and industry partners. The project aims to investigate the use of curved sheet material
Asut, Serdar +3 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Social Housing: Chatsworth Gardens, Ashchurch Place, Fleet Street Hill, Baden Powell Close, Hannibal Road Gardens [PDF]
, 2012 This return comprises five social housing projects undertaken by Peter Barber between 2009 and 2013, some built, some unbuilt. The un-built projects contribute significantly to the development of Barber’s research agenda over this period.
Barber, P., Barber, P.
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Design Research in Cyber-Physical Systems through Weak-Bisimulation [PDF]
Journal of Systemics, Cybernetics and Informatics, 2011 Bisimulation methods for design and verification of complex digital electronics have become well established in engineering practice. Concurrently, there have been dramatic theoretical advances in the theory of hybrid dynamical systems.
Roy Mccann, Khalid Rahman
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source