Results 131 to 140 of about 5,765,787 (386)

Effects of Substrate Preheating Temperatures on the Microstructure, Properties, and Residual Stress of 12CrNi2 Prepared by Laser Cladding Deposition Technique

open access: yesMaterials, 2018
The 12CrNi2 alloy steel powder studied in the present paper is mainly used to manufacture camshafts for nuclear power emergency diesel engines. Laser cladding deposition is of great significance for the manufacture of nuclear power emergency diesel ...
C. Ding, X. Cui, J. Jiao, P. Zhu
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

THE DETERMINNATION OF RESIDUAL STRESS OF GEAR TOOTH ROOT BASED ON X-RAY TECHNOLOGY

open access: yesJixie qiangdu, 2017
Transverse residual stress of tooth root has significant influence on bending fatigue strength of gears.But given the geometry of gears,using the method of exposing teeth root to complete determination of transverse residual stress at present,it not only
WANG Zhen   +3 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Research on Dynamic Evolution of Residual Stress Based on Simulation of Piston Manufacturing Process

open access: yesMetals
Rather than focusing on the residual stress generated from casting, machining, or heat treatment unilaterally, a comprehensive research method to consider the whole dynamic evolution of residual stress is proposed.
Dong Yang   +3 more
doaj   +1 more source

Formation of Residual Stresses during Discontinuous Friction Treatment [PDF]

open access: diamond, 2021
Ihor Hurey   +3 more
openalex   +1 more source

Application of Cryogenic Treatment to Extend the Life of the TiAlN-Coated Tungsten Carbide Milling Cutter [PDF]

open access: yes, 2020
Cutting tools are important to the manufacturing industry since they will affect production efficiency and product quality. Cryogenic treatment can improve the material properties by decreasing residual stress, stabilizing dimensional accuracy, and ...
Hsiung J. -C., Kung H. -K., Wu J. -H.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Experimental determination of residual stress [PDF]

open access: yes
Residual stresses in finished parts have often been regarded as factors contributing to premature part failure and geometric distortions. Currently, residual stresses in welded structures and railroad components are being investigated.
Ferguson, Milton W.
core   +1 more source

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