Results 51 to 60 of about 290,922 (313)
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Phase Chemistry of Tank Sludge Residual Components [PDF]
About four or five distinct reprocessing technologies were used at various times in Hanford's history. After removing U and Pu (or later 137Cs and 90Sr), the strongly acidic HLW was ''neutralized'' to high pH (>13) and stored in steel-lined tanks. High pH was necessary to prevent tank corrosion. While each technology produced chemically distinct waste,
Krumhansl, James L., Nagy, Kathryn L.
openaire +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Understanding biophysical and biochemical processes in detritusphere is critical to quantifying and modeling plant residue decomposition dynamics and subsequent soil organic carbon (C) accrual.
Kyungmin Kim+3 more
doaj
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka+6 more
wiley +1 more source
Persistence of benthiocarb in soil: influence of ultraviolet and sunlight
Persistence of benthiocarb in soil as affected by UV and sunlight exposure was studied. Treated soil was placed in petri plate, brought to field capacity moisture and then exposed to UV and sunlight.
Md. Wasim Aktar+2 more
doaj
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley+2 more
wiley +1 more source
Chlorpyriphos 20 EC was applied at the rate of 500 g a.i. ha-1 in Cabbage heads and the samples harvested at intervals of 0 (2 hours after application), 1 and 7 days after application.
Md. Wasim Aktar+3 more
doaj
Polymers Interfacing with Biology
The development of various controlled radical polymerization techniques as well as site- and residue specific strategies to modify peptides/proteins with synthetic polymers have made polymer chemistry a powerful tool to address materials ...
Frederik Wurm, Harm-Anton Klok
doaj +1 more source