Results 31 to 40 of about 90,229,355 (301)

The zebrafish model to identify new genes involved in thyroid development [PDF]

open access: yes, 2010
Thyroid organogenesis is a very complex developmental process that leads to the formation of an organ able to produce specific hormones through specification, migration, structural organization and functional differentiation of thyroid precursor cells ...
Porreca, Immacolata
core   +1 more source

Thyroid hormones as potential prognostic factors in sepsis [PDF]

open access: yes, 2019
Background: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host reaction to infection. There is an upward trend in sepsis prevalence and mortality worldwide.
Alicja Dudek   +11 more
core   +1 more source

Association of serum level of interleukin-33 and insulin resistance in overt and subclinical hypothyroidism patients

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2023
Hypothyroidism is a condition that occurs when the thyroid gland fails to produce an adequate amount of the hormone thyroid, as a result of factors for example hypothalamic or pituitary gland disease, common tissue resistance to thyroid hormones, and ...
Zainab Abdul Hussein Jabbar   +3 more
doaj   +1 more source

RESISTANCE TO THYROID HORMONE DUE TO A NOVEL THR- MUTATION IN A PATIENT WITH THYROID AGENESIS

open access: yes, 2018
Refetoff Syndrome is a rare disorder characterized by resistance to thyroid hormone (RTH). The coexistence of RTH and thyroid dysgenesis is a rare event. Up to now, only four cases of ectopic gland and RTH have been reported.
Maria Scavone
core   +1 more source

Thyroid gland dysfunction and its effect on the cardiovascular system: a comprehensive review of the literature

open access: yesEndokrynologia Polska, 2020
There is an intimate and functional relationship between the cardiovascular system and the thyroid gland; from sharing the same embryologic origin to modulating each of the components of the heart for a normal function. Due to this relationship, patients
Navid Ahmadi   +4 more
doaj   +1 more source

Does Tribulus terrestris L. affect hormonal responses following high-intensity resistance exercise?

open access: yesBiomedical Human Kinetics, 2022
Study aim: To investigate the effect of a 2-week supplementation with Tribulus terrestris L. (TT) on the responses of testosterone, cortisol, and thyroid hormones including triiodothyronine (T3) and thyroxine (T4) following an intensive session of ...
Ardakani Seyed Mojtaba Paydar   +5 more
doaj   +1 more source

Thyroid Hormone Plays an Important Role in Cardiac Function: From Bench to Bedside

open access: yesFrontiers in Physiology, 2021
Thyroid hormones (THs) are synthesized in the thyroid gland, and they circulate in the blood to regulate cells, tissues, and organs in the body. In particular, they exert several effects on the cardiovascular system.
Hiroyuki Yamakawa   +7 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Associations between the levels of thyroid hormones and abdominal obesity in euthyroid post-menopausal women

open access: yesEndokrynologia Polska, 2020
INTRODUCTION: The aim of this study was to explore the association between thyroid hormones and abdominal fat quantities in euthyroid post-menopausal women.
Qiu Yang   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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