Results 41 to 50 of about 90,229,355 (301)
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Zanco Journal of Pure and Applied Sciences, 2019 Carbimazole is one of the common antithyroid drugs for the treatment of hyperthyroidism. It interferes with the synthesis of thyroid hormones and results in the reducing of thyroid hormones level.
Bnar S Shexane, Muslih A. Ibrahim
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Relationship of thyroid hormones and metabolic parameters in euthyroid women
Turkish Journal of Family PracticeObjective: Thyroid hormones play a role in metabolic regulation, yet their associations with obesity and insulin resistance in euthyroid individuals remain unclear. This study aimed to evaluate the relationship between thyroid-stimulating hormone (TSH),
Fatma Nur Yürekten Sıcakyüz +3 more
doaj +1 more source
Why Can Insulin Resistance Be a Natural Consequence of Thyroid Dysfunction? [PDF]
, 2011 Evidence for a relationship between T4 and T3 and glucose metabolism appeared over 100 years ago when the influence of thyroid hormone excess in the deterioration of glucose metabolism was first noticed. Since then, it has been known that hyperthyroidism
Gabriela Brenta
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Dialogues in Clinical Neuroscience & Mental Health, 2018 Hypothyroidism, more commonly subclinical, appears a common abnormality, while the hypothalamic-pituitary-thyroid (HPT) axis abnormalities are quite common among patients with bipolar disorder.
Orestis Giotakos
doaj +1 more source
Alopecia: Association with Resistance to Thyroid Hormones
Journal of Pediatric Endocrinology and Metabolism, 2009 Resistance to thyroid hormone (RTH) syndrome is caused by thyroid hormone beta receptor (TRbeta) mutations. Goiter, learning disabilities, psychological abnormalities, sinus tachycardia, hearing deficits, short stature, and growth delay are among the most common symptoms in patients with RTH.
Güran, Tülay +3 more
openaire +5 more sources
Advanced Science, EarlyView.The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo +20 more
wiley +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source