Results 71 to 80 of about 18,321 (309)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Transverse barrier formation by electrical triggering of a metal-to-insulator transition

Nature Communications, 2021
Resistive switching usually occurs by the formation of conducting filaments in the direction of current flow. Here the authors study an intriguing type of volatile metal-to-insulator resistive switching in (La,Sr)MnO3, which occurs by the formation of an
Pavel Salev, Lorenzo Fratino, Dayne Sasaki, Rani Berkoun, Javier del Valle, Yoav Kalcheim, Yayoi Takamura, Marcelo Rozenberg, Ivan K. Schuller   +8 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A new opportunity for the emerging tellurium semiconductor: making resistive switching devices

Nature Communications, 2021
Resistive switching devices have great promise for a wide variety of technological applications. Here, Yang et al demonstrate that electrochemically induced tellurium filament can give rise to resistive switching, and show that devices based on this can ...
Yifei Yang, Mingkun Xu, Shujing Jia, Bolun Wang, Lujie Xu, Xinxin Wang, Huan Liu, Yuanshuang Liu, Yuzheng Guo, Lidan Wang, Shukai Duan, Kai Liu, Min Zhu, Jing Pei, Wenrui Duan, Dameng Liu, Huanglong Li   +16 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Electrically stimulated resistive switching in Ag/PEG nanofluids

The dataset contains data on resistive switching due to electrophoretic reorganization of metallic silver (Ag) nanoparticles in polymeric host fluids (i.e. polyethylene glycol of different molecular weight).
Biliak, Kateryna, Nikitin, Daniil, Protsak, Mariia, Adejube, Blessing, Vahl, Alexander   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Resistive switching behaviour.

, 2022
a) Cyclic voltage pattern, showing resistive switching behaviour and an ON/OFF ratio of around 81 at a Read voltage of 1.5 V. b) HRS and LRS currents at Read voltage of 1.5 V for each cycle.
Sören Kaps (508793), Franz Faupel (1578223), Pia Holtz (12329414), Niko Carstens (10326880), Alexander Vahl (6900746), Maik-Ivo Terasa (6900743), Rainer Adelung (301901)   +6 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Zeno Paradox: Some Well-known Nonlinear Dopant Drift Memristor Models Have Infinite Resistive Switching Time [PDF]

Radioengineering, 2023
There are nonlinear drift memristor models utilizing window functions in the literature. The resistive memories can also be modeled using memristors. If the memristor’s resistance switches from its minimum value to its maximum value or from its maximum ...
R. Mutlu, T. D. Kumru
doaj