Results 71 to 80 of about 18,536 (211)

The association between early life antibiotic exposure and the gut resistome of young children: a systematic review

Gut Microbes, 2022
Antimicrobial resistance is a growing public health burden, but little is known about the effects of antibiotic exposure on the gut resistome. As childhood (0–5 years) represents a sensitive window of microbiome development and a time of relatively high ...
Rebecca M. Lebeaux, Despina B. Karalis, Jihyun Lee, Hanna C. Whitehouse, Juliette C. Madan, Margaret R. Karagas, Anne G. Hoen   +6 more
doaj   +1 more source

Discordant transmission of bacteria and viruses from mothers to babies at birth [PDF]

, 2019
BACKGROUND: The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Handley, Scott A, Holtz, Lori R, Lim, Efrem S, Maqsood, Rabia, Ndao, I. Malick, Rodgers, Rachel, Rodriguez, Cynthia, Tarr, Phillip I, Warner, Barbara B   +8 more
core   +2 more sources

Whole‐Genome Sequence Profiling of Listeria innocua From Different Sources: Implications for Public Health

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The studied strains, LIN_NWU_CNKT and LIN5_NWU_CNKT, exhibit invasiveness, pathogenicity, and MDR profiles. The isolation of these strains from food products and water underscores their significant public health implications, particularly in the context of the “One Health” concept.
Christ‐Donald Kaptchouang Tchatchouang, Daniel Jesuwenu Ajose, Giulia Amagliani, Collins Njie Ateba   +3 more
wiley   +1 more source

Bacterial phylogeny structures soil resistomes across habitats [PDF]

Nature, 2014
Ancient and diverse antibiotic resistance genes (ARGs) have previously been identified from soil, including genes identical to those in human pathogens. Despite the apparent overlap between soil and clinical resistomes, factors influencing ARG composition in soil and their movement between genomes and habitats remain largely unknown. General metagenome
Forsberg, Kevin J, Patel, Sanket, Gibson, Molly K, Lauber, Christian L, Knight, Rob, Fierer, Noah, Dantas, Gautam   +6 more
openaire   +4 more sources

The impacts of viral infection and subsequent antimicrobials on the microbiome-resistome of growing pigs

Microbiome, 2022
Background Antimicrobials are used in food-producing animals for purposes of preventing, controlling, and/or treating infections. In swine, a major driver of antimicrobial use is porcine reproductive and respiratory syndrome (PRRS), which is caused by a ...
Tara N. Gaire, Carissa Odland, Bingzhou Zhang, Tui Ray, Enrique Doster, Joel Nerem, Scott Dee, Peter Davies, Noelle Noyes   +8 more
doaj   +1 more source

The fecal resistome of dairy cattle is associated with diet during nursing. [PDF]

, 2019
Antimicrobial resistance is a global public health concern, and livestock play a significant role in selecting for resistance and maintaining such reservoirs.
DePeters, Edward J, Johnson, Daisy, Lemay, Danielle G, Liu, Jinxin, Maldonado-Gomez, Maria X, Mills, David A, Taft, Diana H, Treiber, Michelle L   +7 more
core   +1 more source

System level network data and models attack cancer drug resistance

British Journal of Pharmacology, Volume 183, Issue 8, Page 1640-1652, April 2026.
Drug resistance is responsible for >90% of cancer related deaths. Cancer drug resistance is a system level network phenomenon covering the entire cell. Small‐scale interactomes and signalling network models of drug resistance guide directed drug development.
Márk Kerestély, Dávid Keresztes, Levente Szarka, Borbála M. Kovács, Klára Schulc, Dániel V. Veres, Peter Csermely   +6 more
wiley   +1 more source

Tetracycline Resistome of the Organic Pig Gut [PDF]

Applied and Environmental Microbiology, 2009
ABSTRACT The occurrence of genes conferring resistance to tetracyclines in the organic pig gut was assessed through the metagenomic approach. Of 9,000 bacterial artificial chromosome clones analyzed, 10 were identified as carrying the known tet (C), tet (W), and tet
Katarzyna A, Kazimierczak, Karen P, Scott, Denise, Kelly, Rustam I, Aminov   +3 more
openaire   +2 more sources

Breastfeeding and the milk resistome shape the establishment and transmission of antibiotic resistance genes in the infant gut microbiome

Gut Microbes
The infant resistome, the collection of antibiotic resistance genes (ARGs) of newborns, is critical for gut microbiota establishment. Using metagenomic sequencing data, we analyzed various 1-week and 1-month postpartum samples to study infant resistome ...
Zhe Pan, Calum J. Walsh, Conor Feehily, Sai Ravi Chandra Nori, Fionnuala M. McAuliffe, Paul D. Cotter, John MacSharry, Douwe van Sinderen   +7 more
doaj   +1 more source

Population-level impacts of antibiotic usage on the human gut microbiome

Nature Communications, 2023
Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both ...
Kihyun Lee, Sebastien Raguideau, Kimmo Sirén, Francesco Asnicar, Fabio Cumbo, Falk Hildebrand, Nicola Segata, Chang-Jun Cha, Christopher Quince   +8 more
doaj   +1 more source