Results 11 to 20 of about 423,838 (252)

Resolution of inflammation during rheumatoid arthritis [PDF]

open access: yesFrontiers in Cell and Developmental Biology
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes synovial joint inflammation as well as bone destruction and erosion, typically characterized by joint pain, swelling, and stiffness, with complications and persistent pain after ...
Xiaoou Ye   +8 more
doaj   +2 more sources

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation [PDF]

open access: yesFrontiers in Immunology, 2022
Several chronic inflammatory diseases are associated with non-resolving inflammation. Conventional anti-inflammatory drugs fail to completely cure these diseases.
Philippe Saas   +6 more
doaj   +2 more sources

Ribonucleic Acid Sequencing Reveals the Upregulation and Resolution of Inflammation and Extracellular Matrix Remodeling in Lidocaine-Treated Human Acute Monocytic Leukemia Cell Line THP-1 [PDF]

open access: yesBiomedicines
Lidocaine, a local anesthetic widely used in dentistry, is esteemed for its efficacy and safety. Recent research reveals its additional role in modulating the immune system, and particularly in reducing inflammation crucial for protecting tooth ...
Sheng-Wei Feng   +4 more
doaj   +2 more sources

Platelets in Inflammation and Resolution [PDF]

open access: yesThe Journal of Immunology, 2019
Abstract Platelets have long been known for their role in hemostasis. In this, platelet adhesion and activation leads to the formation of a firm thrombus and thus the sealing of a damaged blood vessel. More recently, inflammatory modes of function have been attributed to these non–nuclei-containing cellular fragments.
Andreas Margraf, Alexander Zarbock
openaire   +2 more sources

Efferocytosis during Skeletal Muscle Regeneration

open access: yesCells, 2021
Efferocytosis, i.e., engulfment of dead cells by macrophages, is a crucial step during tissue repair after an injury. Efferocytosis delineates the transition from the pro-inflammatory phase of the inflammatory response to the recovery phase that ensures ...
Gaëtan Juban, Bénédicte Chazaud
doaj   +1 more source

Resolution of Inflammation in Asthma [PDF]

open access: yesClinics in Chest Medicine, 2012
The resolution of inflammation in healthy airways is an active process, with specialized mediators and cellular mechanisms enlisted to restore tissue homeostasis. This article focuses on recent discoveries of natural mediators derived from essential fatty acids, including ω-3 fatty acids, with anti-inflammatory and pro-resolving.
Bruce D, Levy   +2 more
openaire   +2 more sources

Role of Tristetraprolin in the Resolution of Inflammation [PDF]

open access: yesBiology, 2021
Inflammation is a crucial part of immune responses towards invading pathogens or tissue damage. While inflammatory reactions are aimed at removing the triggering stimulus, it is important that these processes are terminated in a coordinate manner to prevent excessive tissue damage due to the highly reactive inflammatory environment.
Peter Rappl   +2 more
openaire   +4 more sources

Stimulating the Resolution of Inflammation Through Omega-3 Polyunsaturated Fatty Acids in COVID-19: Rationale for the COVID-Omega-F Trial

open access: yesFrontiers in Physiology, 2021
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 triggers an immune response with local inflammation in the lung, which may extend to a systemic hyperinflammatory reaction.
Hildur Arnardottir   +16 more
doaj   +1 more source

11,12-EET Regulates PPAR-γ Expression to Modulate TGF-β-Mediated Macrophage Polarization

open access: yesCells, 2023
Macrophages are highly plastic immune cells that can be reprogrammed to pro-inflammatory or pro-resolving phenotypes by different stimuli and cell microenvironments.
Xiaoming Li   +4 more
doaj   +1 more source

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