Results 21 to 30 of about 423,838 (252)

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

Frontiers in Pharmacology, 2022
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15 ...
Nils Helge Schebb, Hartmut Kühn, Astrid S. Kahnt, Katharina M. Rund, Valerie B. O’Donnell, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Karsten H. Weylandt, Nadine Rohwer, Nadine Rohwer, Robert C. Murphy, Gerd Geisslinger, Gerd Geisslinger, Garret A. FitzGerald, Julien Hanson, Julien Hanson, Claes Dahlgren, Mohamad Wessam Alnouri, Stefan Offermanns, Stefan Offermanns, Dieter Steinhilber, Dieter Steinhilber   +22 more
doaj   +1 more source

Natural resolution of inflammation [PDF]

Periodontology 2000, 2013
AbstractInflammation is a protective response essential for maintaining human health and for fighting disease. As an active innate immune reaction to challenge, inflammation gives rise to clinical cardinal signs: rubor, calor, dolor, tumor and functio laesa.
Marcelo O, Freire, Thomas E, Van Dyke
openaire   +2 more sources

A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution

Frontiers in Immunology, 2018
During the resolution of inflammation, macrophages engulf apoptotic polymorphonuclear cells (PMN) and can accumulate large numbers of their corpses. Here, we report that resolution phase macrophages acquire the neutrophil-derived glycoprotein lactoferrin
Aviv Lutaty, Aviv Lutaty, Soaad Soboh, Soaad Soboh, Sagie Schif-Zuck, Sagie Schif-Zuck, Orly Zeituni-Timor, Orly Zeituni-Timor, Ran Rostoker, Ran Rostoker, Malgorzata J. Podolska, Christine Schauer, Martin Herrmann, Luis E. Muñoz, Amiram Ariel, Amiram Ariel   +15 more
doaj   +1 more source

Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Leukocyte‐directed biosynthesis of specialized proresolving mediators (SPMs) orchestrates physiological inflammation after myocardial infarction.
Amanda B. Pullen, Vasundhara Kain, Charles N. Serhan, Ganesh V. Halade   +3 more
doaj   +1 more source

Inflammation and Atrial Fibrillation

Journal of Arrhythmia, 2011
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice. Accumulating evidence indicates a link between inflammation and AF, and important advances in understanding mechanisms of AF are arising from studies of ...
Yasumi Endoh, MD PhD, Ikuko Endoh, MD PhD, Carolyn Geczy, PhD, Akihiro Nakagomi, MD PhD, Yoshiki Kusama, MD PhD, Hirotsugu Atarashi, MD PhD   +5 more
doaj   +1 more source

The Use of Specialized Pro-Resolving Mediators in Biomaterial-Based Immunomodulation

Journal of Functional Biomaterials, 2023
The implantation of a biomaterial will lead to the immediate onset of an acute inflammatory response, which is of key importance in shaping the quality of the repair process.
Ana Beatriz Sousa, Judite N. Barbosa
doaj   +1 more source

Leukocytes in Inflammation, Resolution of Inflammation, Autoimmune Diseases and Cancer

Cells, 2021
Inflammation is a double-edged sword [...]
János G. Filep
doaj   +1 more source

Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?

Cells, 2023
So far, tendon regeneration has mainly been analyzed independent from its adjacent tissues. However, the subacromial bursa in particular appears to influence the local inflammatory milieu in the shoulder.
Franka Klatte-Schulz, Nicole Bormann, Aysha Bonell, Jasmin Al-Michref, Hoang Le Nguyen, Pascal Klöckner, Kathi Thiele, Philipp Moroder, Martina Seifert, Birgit Sawitzki, Britt Wildemann, Georg N. Duda   +11 more
doaj   +1 more source

Effects of Myrcia splendens extract on innate inflammatory response [PDF]

Rodriguésia
This study investigated the anti-inflammatory activity of the crude hydroalcoholic extract of Myrcia splendens leaves. In vitro, neutrophil chemotaxis and LPS-induced inflammatory mediators were assessed in neutrophils or macrophages treated with M ...
Mayra Alice Corrêa Pitz, Larissa Benvenutti, Camila Jeriane Paganelli, Thaynara Reichert, Nara Lins Meira Quintão, Michele Debiasi Alberton, José Roberto Santin, Isabel Daufenback Machado   +7 more
doaj   +2 more sources

Omega-3 Polyunsaturated Fatty Acids and the Resolution of Inflammation: Novel Therapeutic Opportunities for Aortic Valve Stenosis?

Frontiers in Cell and Developmental Biology, 2020
Inflammation is well-established in cardiovascular disease, including valvular heart disease. Inflammation is a key process in the fibrosis and calcification of the aortic valve leaflets, which ultimately clinically manifest as aortic valve stenosis ...
Gonzalo Artiach, Magnus Bäck, Magnus Bäck   +2 more
doaj   +1 more source