Results 231 to 240 of about 675,824 (339)

How sphingolipids affect T cells in the resolution of inflammation. [PDF]

open access: yesFront Pharmacol, 2022
Hartel JC, Merz N, Grösch S.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. [PDF]

open access: yesJ Clin Invest, 2023
Rathod KS   +15 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

HUMANIN produced by human efferocytic macrophages promotes the resolution of inflammation. [PDF]

open access: yesCell Death Dis
Maraux M   +10 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Prolonged Aggressive Experience Accelerates Resolution of Inflammation in Blood and Microglia After Repeated LPS Treatment. [PDF]

open access: yesInt J Mol Sci
Mutovina A   +7 more
europepmc   +1 more source

CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation. [PDF]

open access: yesFront Immunol, 2023
Peckert-Maier K   +12 more
europepmc   +1 more source

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