Results 221 to 230 of about 422,920 (251)
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DELineating resolution of inflammation
Nature Immunology, 2018The resolution of inflammation is a protective response. The identification and characterization of new players that boost this response might inform the development of novel therapies for non-resolving inflammatory diseases.
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The role of neutrophils in inflammation resolution
Seminars in Immunology, 2016The fundamental role played by neutrophils for an efficient, acute inflammatory response has long been appreciated, with the underlying molecular and cellular mechanisms largely elucidated over the past decades. However, more recent work suggests that the biological functions exerted by this fascinating leucocyte are somewhat more extensive than ...
Hefin R. Jones +3 more
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1988
For centuries, the inflammatory response has been regarded as an important consequence of injury and one that normally leads to repair and restoration of function. From the battlefield observations of John Hunter in 1794 to the elegant vascular studies of Cohnheim (1889) and the descriptions of cell migration by Metchnikoff (1891) a century later, the ...
Christopher Haslett, Peter M. Henson
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For centuries, the inflammatory response has been regarded as an important consequence of injury and one that normally leads to repair and restoration of function. From the battlefield observations of John Hunter in 1794 to the elegant vascular studies of Cohnheim (1889) and the descriptions of cell migration by Metchnikoff (1891) a century later, the ...
Christopher Haslett, Peter M. Henson
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COX-2 in Inflammation and Resolution
Molecular Interventions, 2006Aspirin and the other NSAIDs have popularized the notion of inhibiting prostaglandins as a common anti-inflammatory strategy based on the erroneous premise that all eicosanoids are, within the context of inflammation, generally detrimental. However, our fascination with aspirin and the emergence of COX-2 has shown a more affable side to lipid mediators
Ravindra, Rajakariar +2 more
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Initiation and Resolution of Mucosal Inflammation
Immunologic Research, 2004Antigens entering the body through the mucosal surface are screened by a highly developed immune system comprised not only of traditional lymphoid cells but also epithelial cells, fibroblasts, and antigen-presenting cells (APCs). For example, in the intestinal tract, gut-associated lymphoid tissue (GALT) is tolerant to the approx 400 separate commensal
Melanie A, Sherman, Daniel, Kalman
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Resolution of Lung Inflammation by CD44
Science, 2002Successful repair after tissue injury and inflammation requires resolution of the inflammatory response and removal of extracellular matrix breakdown products. We have examined whether the cell-surface adhesion molecule and hyaluronan receptor CD44 plays a role in resolving lung inflammation.
Priit, Teder +7 more
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2006
Inflammation requires clearance of the inciting pathogen, then orchestrated removal of the burden of leukocytes and other cells influxed into the inflamed site along with dissipation of the pro (or anti) inflammatory mediator cascades. We now recognize that this resolution process is strictly controlled by a number of mediators and adhesion molecules ...
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Inflammation requires clearance of the inciting pathogen, then orchestrated removal of the burden of leukocytes and other cells influxed into the inflamed site along with dissipation of the pro (or anti) inflammatory mediator cascades. We now recognize that this resolution process is strictly controlled by a number of mediators and adhesion molecules ...
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Cellular resolution of inflammation—catabasis
Wound Repair and Regeneration, 2012AbstractControlled inflammation has become a central focus in chronic disease therapeutics. Exaggerated inflammation is a common factor that contributes to matrix destruction, cellular senescence, and nonhealing in a variety of disease processes. Efforts at controlling inflammation have traditionally concentrated on systemic antagonists to inflammation
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Lipoxins, Resolvins, and the Resolution of Inflammation
2016Resolution of acute inflammation is an active process, where endogenous specialized pro-resolving mediators (SPM), derived from polyunsaturated fatty acids via lipoxygenase (LO)-driven biochemical pathways, have pivotal roles in “turning off” pro-inflammatory signals, prompting timely resolution.
RECCHIUTI, ANTONIO +3 more
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The Resolution of Inflammation
Inflammopharmacology, 2008Adriano G. Rossi, Deborah A. Sawatsky
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