Results 211 to 220 of about 422,920 (251)
The effect of ageing on the resolution of inflammation
Ageing Research Reviews, 2020 Ageing is associated with the development of a low-level, systemic, chronic inflammation known as "inflammaging". This chronic inflammatory state can contribute to diseases of ageing such as sarcopenia and frailty. The presence of inflammaging suggests a failure of the cell clearance mechanisms that ordinarily aid in the resolution of inflammation ...
Wezi Sendama
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Resolvins and Protectins in Inflammation Resolution [PDF]
Chemical Reviews, 2011 The critical role of inflammatory processes in health and disease has long been recognized,1 yet the detailed molecular mechanisms and biological events that regulate the progression and resolution of inflammation remain of interest. A number of recent investigations have provided strong evidence that the resolution of inflammation is not a passive ...
Charles N Serhan, Nicos A Petasis
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Lipoxin Mimetics and the Resolution of Inflammation
Annual Review of Pharmacology and Toxicology, 2023 Inflammation and its timely resolution are critical to ensure effective host defense and appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation typifies many prevalent pathologies. The key mediators that initiate and drive the inflammatory response are well defined and targeted by conventional anti-inflammatory ...
Catherine Godson, Eoin P Brennan
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International Journal of Immunopharmacology, 2000
Acute inflammatory reactions, in contrast to chronic inflammatory reactions, are usually self-limiting and resolve. We have investigated the resolving phase of a number of immune and non-immune inflammatory reactions induced in the pleural cavity of rats. COX-2 is expressed during resolution of these models.
D A, Willoughby +3 more
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Acute inflammatory reactions, in contrast to chronic inflammatory reactions, are usually self-limiting and resolve. We have investigated the resolving phase of a number of immune and non-immune inflammatory reactions induced in the pleural cavity of rats. COX-2 is expressed during resolution of these models.
D A, Willoughby +3 more
openaire +2 more sources
The resolution of inflammation and cancer
Cytokine & Growth Factor Reviews, 2010Inflammation has long been thought to contribute to the development of cancer; however there is also clear evidence that the immune system can recognize and eliminate cancer cells. Current research suggests that cancer-associated inflammation has a dual role in tumor progression; inflammatory mediators promote the malignant activity of cancer cells by ...
Rodriguez-Vita, Juan, Lawrence, Toby
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The Atlas of Inflammation Resolution (AIR)
Molecular Aspects of Medicine, 2020 Acute inflammation is a protective reaction by the immune system in response to invading pathogens or tissue damage. Ideally, the response should be localized, self-limited, and returning to homeostasis. If not resolved, acute inflammation can result in organ pathologies leading to chronic inflammatory phenotypes.
Charles N Serhan +2 more
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Resolution of inflammation in oral diseases
Pharmacology & Therapeutics, 2023The resolution of inflammation is an essential endogenous process that protects host tissues from an exaggerated chronic inflammatory response. Multiple interactions between host cells and resident oral microbiome regulate the protective functions that lead to inflammation in the oral cavity.
Eiba G, Eltay, Thomas, Van Dyke
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Inflammation and resolution in obesity
Nature Reviews EndocrinologyInflammation is an essential physiological defence mechanism, but prolonged or excessive inflammation can cause disease. Indeed, unresolved systemic and adipose tissue inflammation drives obesity-related cardiovascular disease and type 2 diabetes mellitus.
Matúš Soták +3 more
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Resolution of inflammation in arthritis
Seminars in Immunopathology, 2019Rheumatoid arthritis is among the most frequent and severe chronic inflammatory diseases. The disease is characterized by ongoing synovial inflammation, which leads to the destruction of cartilage and bone. In RA, the mechanisms of resolution of inflammation, which are normally intact in the joints, are either suppressed or overruled.
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Triggering and resolution of inflammation in NASH
Nature Reviews Gastroenterology and Hepatology, 2018Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular injury and different degrees of fibrosis. A central issue in this field relates to the identification of those factors that trigger inflammation, thus fuelling the ...
Daniel Cabrera +2 more
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