Results 31 to 40 of about 675,824 (339)

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.

Immunity, 2021
Alternatively activated macrophages (AAMs) contribute to the resolution of inflammation and tissue repair. However, molecular pathways that govern their differentiation have remained incompletely understood.
Maria Faas, N. Ipseiz, Jochen A. Ackermann, S. Culemann, Anika Grüneboom, F. Schröder, T. Rothe, C. Scholtysek, M. Eberhardt, M. Böttcher, Philipp Kirchner, Cornelia Stoll, A. Ekici, M. Fuchs, Meik Kunz, B. Weigmann, S. Wirtz, R. Lang, J. Hofmann, J. Vera, D. Voehringer, A. Michelucci, D. Mougiakakos, S. Uderhardt, G. Schett, G. Krönke   +25 more
semanticscholar   +1 more source

Resolution of Inflammation in Periodontitis [PDF]

Journal of Periodontology, 2005
Chronic inflammatory illnesses such as diabetes, arthritis, and heart disease are now seen as problems that might have impacts on the periodontium, and reciprocal effects of periodontal diseases are being considered as factors potentially affecting the progression of these diseases.
Alpdogan, Kantarci, Thomas E, Van Dyke
openaire   +3 more sources

Stimulating the Resolution of Inflammation Through Omega-3 Polyunsaturated Fatty Acids in COVID-19: Rationale for the COVID-Omega-F Trial

Frontiers in Physiology, 2021
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 triggers an immune response with local inflammation in the lung, which may extend to a systemic hyperinflammatory reaction.
Hildur Arnardottir, Hildur Arnardottir, Sven-Christian Pawelzik, Sven-Christian Pawelzik, Ulf Öhlund Wistbacka, Gonzalo Artiach, Gonzalo Artiach, Robin Hofmann, Robin Hofmann, Ingalill Reinholdsson, Frieder Braunschweig, Per Tornvall, Per Tornvall, Dorota Religa, Dorota Religa, Magnus Bäck, Magnus Bäck   +16 more
doaj   +1 more source

11,12-EET Regulates PPAR-γ Expression to Modulate TGF-β-Mediated Macrophage Polarization

Cells, 2023
Macrophages are highly plastic immune cells that can be reprogrammed to pro-inflammatory or pro-resolving phenotypes by different stimuli and cell microenvironments.
Xiaoming Li, Sebastian Kempf, Stefan Günther, Jiong Hu, Ingrid Fleming   +4 more
doaj   +1 more source

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Resolution of inflammation is an active process that restores tissue homeostasis and prevents the development of chronic inflammatory diseases. The mechanisms that regulate resolution of inflammation are only partially understood.
A. Caravaca, A. Gallina, L. Tarnawski, V. S. Shavva, R. Colas, Jesmond Dalli, S. Malin, Henrik Hult, H. Arnardottir, P. Olofsson   +9 more
semanticscholar   +1 more source

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

Frontiers in Pharmacology, 2022
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15 ...
Nils Helge Schebb, Hartmut Kühn, Astrid S. Kahnt, Katharina M. Rund, Valerie B. O’Donnell, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Karsten H. Weylandt, Nadine Rohwer, Nadine Rohwer, Robert C. Murphy, Gerd Geisslinger, Gerd Geisslinger, Garret A. FitzGerald, Julien Hanson, Julien Hanson, Claes Dahlgren, Mohamad Wessam Alnouri, Stefan Offermanns, Stefan Offermanns, Dieter Steinhilber, Dieter Steinhilber   +22 more
doaj   +1 more source

Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy.

Kidney International, 2021
Since failed resolution of inflammation is a major contributor to the progression of diabetic nephropathy, identifying endogenously generated molecules that promote the physiological resolution of inflammation may be a promising therapeutic approach for ...
Liang Wu, Changjie Liu, D. Chang, Rui Zhan, Jinghua Sun, Shi-he Cui, S. Eddy, V. Nair, E. Tanner, F. Brosius, H. Looker, R. Nelson, M. Kretzler, Jiancheng Wang, Ming Xu, W. Ju, Ming-Hui Zhao, Min Chen, Lemin Zheng   +18 more
semanticscholar   +1 more source

Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Leukocyte‐directed biosynthesis of specialized proresolving mediators (SPMs) orchestrates physiological inflammation after myocardial infarction.
Amanda B. Pullen, Vasundhara Kain, Charles N. Serhan, Ganesh V. Halade   +3 more
doaj   +1 more source

Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]

, 2020
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L., Battaglia, R., Bruno, G., Ciardi, M. R., Corazziari, E. S., de Angelis, M., Iera, J., Mascellino, M. T., Mastroianni, C. M., Miele, M. C., Morelli, S., Oliva, A., Venditti, M., Vullo, V.   +13 more
core   +1 more source

A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution

Frontiers in Immunology, 2018
During the resolution of inflammation, macrophages engulf apoptotic polymorphonuclear cells (PMN) and can accumulate large numbers of their corpses. Here, we report that resolution phase macrophages acquire the neutrophil-derived glycoprotein lactoferrin
Aviv Lutaty, Aviv Lutaty, Soaad Soboh, Soaad Soboh, Sagie Schif-Zuck, Sagie Schif-Zuck, Orly Zeituni-Timor, Orly Zeituni-Timor, Ran Rostoker, Ran Rostoker, Malgorzata J. Podolska, Christine Schauer, Martin Herrmann, Luis E. Muñoz, Amiram Ariel, Amiram Ariel   +15 more
doaj   +1 more source