Results 41 to 50 of about 675,824 (339)

The Use of Specialized Pro-Resolving Mediators in Biomaterial-Based Immunomodulation

Journal of Functional Biomaterials, 2023
The implantation of a biomaterial will lead to the immediate onset of an acute inflammatory response, which is of key importance in shaping the quality of the repair process.
Ana Beatriz Sousa, Judite N. Barbosa
doaj   +1 more source

Tilting the Balance: Therapeutic Prospects of CD83 as a Checkpoint Molecule Controlling Resolution of Inflammation

International Journal of Molecular Sciences, 2022
Chronic inflammatory diseases and transplant rejection represent major challenges for modern health care. Thus, identification of immune checkpoints that contribute to resolution of inflammation is key to developing novel therapeutic agents for those ...
Katrin Peckert-Maier, Dmytro Royzman, Pia Langguth, Anita Marosan, Astrid Strack, Atefeh Sadeghi Shermeh, A. Steinkasserer, E. Zinser, A. Wild   +8 more
semanticscholar   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2013
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross, A G Rossi, A Planaguma, AE Leitch, AE Leitch, AG Rossi, AL Alessandri, B Dibbert, BM Fournier, C Akgul, C D Lucas, C Haslett, C Nathan, C T Robb, CD Lucas, CN Serhan, D A Dorward, DA Dorward, DA Moulding, DA Moulding, DA Steimer, DJ Wardle, E Abraham, EE McGrath, GL Bannenberg, GS Worthen, H Liu, HG Folkesson, HM Marriott, I Dzhagalov St, I Nicoletti, J A Marwick, J Liang, JS Savill, K C Allen, K Ganeshan, KP Steinberg, L Fialkow, L Santo, M A Tait, MA Matthay, N Chiang, N Fotouhi-Ardakani, N Hirani, O Eickmeier, R Boxio, R Duffin, S Brode, S Fox, S Fox, S Michlewska, SJ Leuenroth, SL Poe, SP Garrison, T Hideshima, T Tanaka, TR Ulich, U Koedel, Y Liu   +58 more
core   +1 more source

Anti-Inflammatory Function of Fatty Acids and Involvement of Their Metabolites in the Resolution of Inflammation in Chronic Obstructive Pulmonary Disease

International Journal of Molecular Sciences, 2021
Lipid metabolism plays an important role in many lung functions. Disorders of lipid metabolism are part of the pathogenesis of chronic obstructive pulmonary disease (COPD). Lipids are involved in numerous cross-linkages with inflammation.
S. Kotlyarov, A. Kotlyarova
semanticscholar   +1 more source

Inflammation and Atrial Fibrillation

Journal of Arrhythmia, 2011
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice. Accumulating evidence indicates a link between inflammation and AF, and important advances in understanding mechanisms of AF are arising from studies of ...
Yasumi Endoh, MD PhD, Ikuko Endoh, MD PhD, Carolyn Geczy, PhD, Akihiro Nakagomi, MD PhD, Yoshiki Kusama, MD PhD, Hirotsugu Atarashi, MD PhD   +5 more
doaj   +1 more source

Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?

Cells, 2023
So far, tendon regeneration has mainly been analyzed independent from its adjacent tissues. However, the subacromial bursa in particular appears to influence the local inflammatory milieu in the shoulder.
Franka Klatte-Schulz, Nicole Bormann, Aysha Bonell, Jasmin Al-Michref, Hoang Le Nguyen, Pascal Klöckner, Kathi Thiele, Philipp Moroder, Martina Seifert, Birgit Sawitzki, Britt Wildemann, Georg N. Duda   +11 more
doaj   +1 more source

A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells [PDF]

, 2016
Chronic inflammation can lead to the development of cancers and resolution of inflammation is an ongoing challenge.
Bishop, K. S., Denny, W. A., Ferguson, L. R., Lin, Z., Marlow, Gareth, Murray, P., Sutherland, H.   +6 more
core   +1 more source

Resolution of Inflammation in Asthma [PDF]

Clinics in Chest Medicine, 2012
The resolution of inflammation in healthy airways is an active process, with specialized mediators and cellular mechanisms enlisted to restore tissue homeostasis. This article focuses on recent discoveries of natural mediators derived from essential fatty acids, including ω-3 fatty acids, with anti-inflammatory and pro-resolving.
Bruce D, Levy, Isabelle, Vachier, Charles N, Serhan   +2 more
openaire   +2 more sources

Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease. [PDF]

, 2014
The etiology of persistent lung inflammation in preterm infants with chronic lung disease of prematurity (CLD) is poorly characterized, hampering efforts to stratify prognosis and treatment. Airway macrophages are important innate immune cells with roles
A Kotiranta-Ainamo, AE Currie, BJ Zeligs, BJ Zeligs, BW Kramer, BW Parks, C Haslett, D Chantry, David H. Dockrell, DH Bowden, E Alenghat, E Forster-Waldl, Eamon P. McGreal, ER Unanue, F Genel, F Kanakoudi-Tsakalidou, G Fingerle, G Kurland, H Arai, HM Marriott, HW Ziegler-Heitbrock, HW Zimmermann, HY Huh, Ian Sabroe, J Grigg, J Savill, JA Bellanti, JM Cavaillon, JM Grigg, K Asada, K Dhaliwal, L Landsman, L Ziegler-Heitbrock, LJ Van Marter, Lynne R. Prince, M Daigneault, M Iwahashi, M Zhang, ML Huynh, Moira K. Whyte, NE Alexis, Nicola C. Maxwell, NS Dessardo, O Grip, Oliver Eickelberg, P Antal-Szalmas, PL Davies, R Andreesen, RL Kradin, S Knapp, S Kotecha, S Kotecha, S Rosseau, SA Renshaw, Sailesh Kotecha, SB Gordon, Sharonjit K. Gill, T Ganz, TS Blackwell, U Hallwirth, VA Fadok, WS Driscoll   +61 more
core   +8 more sources

Omega-3 Polyunsaturated Fatty Acids and the Resolution of Inflammation: Novel Therapeutic Opportunities for Aortic Valve Stenosis?

Frontiers in Cell and Developmental Biology, 2020
Inflammation is well-established in cardiovascular disease, including valvular heart disease. Inflammation is a key process in the fibrosis and calcification of the aortic valve leaflets, which ultimately clinically manifest as aortic valve stenosis ...
Gonzalo Artiach, Magnus Bäck, Magnus Bäck   +2 more
doaj   +1 more source