Results 81 to 90 of about 4,958,218 (328)

Optimization of the seed medium of Lactobacillus casei GJ00412 isolated from soy whey

open access: yesLiang you shipin ke-ji, 2020
Soy whey (SW) is generated as a process waste during soy isolate protein preparation. SW has low content of soluble sugar and high content of oligosaccharide, which is suitable for the growth of lactic acid bacteria (LAB).
HAN Wei   +7 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Identification of critical parameters of cell transition from the state of proliferation to the state of differentiation

open access: yesБіологічні студії, 2014
This paper describes by mathematical modeling changes in the genetic control of cell in a state of proliferation and differentiation. It was constructed seventeen response surfaces for each of the speed rate constants that characterize the ...
I. V. Stadnyk, D. I. Sanagursky
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Triggering thresholds and influential factors in the propagation of meteorological drought to hydrological drought

open access: yesJournal of Hydrology: Regional Studies
Study regions: The Huaihe River Basin (HRB), China Study focus: Quantifying the thresholds for the systematic propagation of meteorological drought (MD) to different levels of hydrological drought (HD) is essential for early warning and precision ...
Na Zhen   +5 more
doaj   +1 more source

Leaf nutrient contents of rangpur lime rootstock as afected by N, P, K, Ca and S fertilization Concentrações foliares do porta-enxerto limoeiro 'cravo' em função da adubação N, P, K, Ca e S

open access: yesScientia Agricola, 2004
Analysis of leaf nutrient contents can demonstrate plant nutritional status, identify symptoms of deficiency and toxicity, and evaluate the need to adjust fertilization programs.
Jonas Ruschel   +4 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A Two-Step Reconstruction Framework for Mapping Seamless All-Weather Daily Evapotranspiration Using Thermal Infrared Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Spatio-temporally continuous daily evapotranspiration (ET) is essential for characterizing water and energy exchange and scheduling efficient water management.
Gengle Zhao   +9 more
doaj   +1 more source

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