Results 51 to 60 of about 471,185 (297)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploring the informal learning of zero waste lifestyle in Malaysia with big data analytics

Cleaner and Responsible Consumption
Malaysia's solid waste generation is showing a worrying increasing trend, while public awareness towards achieving zero waste remains low. As a big data resource, social media gives valuable insight into the public's perspective on zero waste and, as ...
Nur Suhaila Zulkifli, Latifah Abd Manaf
doaj   +1 more source

Genetics of caffeine consumption and responses to caffeine [PDF]

Psychopharmacology, 2010
Caffeine is widely consumed in foods and beverages and is also used for a variety of medical purposes. Despite its widespread use, relatively little is understood regarding how genetics affects consumption, acute response, or the long-term effects of caffeine.This paper reviews the literature on the genetics of caffeine from the following: (1) twin ...
Amy, Yang, Abraham A, Palmer, Harriet, de Wit   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Do they know its CSR at all? An exploration of socially responsible music consumption

, 2016
The increasing visibility and elevated status of musicians has become prominent in contemporary society as a consequence of technological advances and the development of both mass and specialized targeted audiences. Consequently, the actions of musicians
Tinson, Julie, Green, Todd, Sinclair, Gary   +2 more
core   +1 more source

Development of a novel psychological model to predict the eco-block building adoption in Mauritius

Cleaner and Responsible Consumption
As a consequence of energy issues and societal dilemmas, building insulation like the eco-block technology has proven its usefulness to reduce greenhouse gas emissions, improve energy security and enhance the living conditions of building occupants.
Hashita Joyram, Kannan Govindan, Robin Nunkoo   +2 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Socially Responsible Consumption of Information Technology Equipment : Case Studies from the Australian Banking Sector [PDF]

Contemporary organizations have been facing increasing pressure to alleviate ecological deterioration through socially responsible consumption—purchase and use of products or services that have positive or less negative social and environmental impact ...
Arslan, Ahmad, Nguyen, Ngoc Dang Khoa, Ali, Imran   +2 more
core   +1 more source

Greek primary school students’ moral judgments and motives about sustainable food consumption

Cleaner and Responsible Consumption
Modern dietary habits pose large threats to the global vision for a sustainable food system transition, intensifying discussions around the urgency for educational initiatives that can promote more sustainable food consumption practices.
Vasiliki Maria Panatsa, Georgios Malandrakis   +1 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source