Results 41 to 50 of about 409,301 (101)

Brain‐Responsive Neurostimulation for the treatment of adults with epilepsy in tuberous sclerosis complex: A case series

Epilepsia Open, 2021
Objective Tuberous sclerosis complex (TSC) is a genetic disorder primarily characterized by the development of multisystem benign tumors. Epilepsy is the most common neurologic manifestation, affecting 80%‐90% of TSC patients.
Danielle S. McDermott, Emily A. Mirro, Kirsten Fetrow, David E. Burdette, Stephanie Chen, Jennifer Hopp, Todd Masel, Emily A. Johnson, Felicia M. K. Elefant, Scheherazade Le, Sanjay E. Patra, Mesha‐Gay Brown, Zulfi Haneef   +12 more
doaj   +1 more source

Intracranial stimulation for pediatric refractory epilepsy: A single institutional experience using evolving therapies

Epilepsia Open
Objective Neuromodulation for pediatric refractory epilepsy (PRE) is preferred when the seizure onset zone is not amenable to surgical resection, due to multifocal onset or involvement of eloquent cortex. Given its rapidly evolving landscape, we describe
Rohin Singh, Megan M. J. Bauman, Karimul Islam, Panagiotis Kerezoudis, Sanjeet S. Grewal, Jonathon J. Parker, Jamie J. Van Gompel, Kai J. Miller, Brian N. Lundstrom, Keith Starnes   +9 more
doaj   +1 more source

Brain‐responsive neurostimulation treatment in patients with GAD65 antibody–associated autoimmune mesial temporal lobe epilepsy

Epilepsia Open, 2020
Glutamic acid decarboxylase 65‐kilodalton isoform (GAD65) antibodies have been associated with multiple nonneurological and neurological syndromes including autoimmune epilepsy (AE). Although immunotherapy remains the cornerstone for the treatment of AE,
Anteneh M Feyissa, Emily A. Mirro, Angela Wabulya, William O. Tatum, Kaitlyn E. Wilmer‐Fierro, Hae Won Shin   +5 more
doaj   +1 more source

Centromedian nucleus targeting in the pediatric population treated with thalamic responsive neurostimulation for drug‐resistant epilepsy

Epilepsia Open
The management of drug‐resistant epilepsy (DRE) in the pediatric population using neurostimulation of the centromedian (CM) nucleus of the thalamus (CMN) has been reported to be effective and safe.
Marian Michael Bercu, Bahram Sarvi Zargar, Kathryn E. Spykman, Gabe Heredia, Alon Y. Mogilner, Angel W. Hernandez, Sanjay E. Patra, David E. Burdette, Paul Ferrari   +8 more
doaj   +1 more source

Resting-state background features demonstrate multidien cycles in long-term EEG device recordings

Brain Stimulation, 2023
Background: Longitudinal EEG recorded by implanted devices is critical for understanding and managing epilepsy. Recent research reports patient-specific, multi-day cycles in device-detected epileptiform events that coincide with increased likelihood of ...
William K.S. Ojemann, Brittany H. Scheid, Sofia Mouchtaris, Alfredo Lucas, Joshua J. LaRocque, Carlos Aguila, Arian Ashourvan, Lorenzo Caciagli, Kathryn A. Davis, Erin C. Conrad, Brian Litt   +10 more
doaj   +1 more source

Stimulation better targets fast-ripple generating networks in super responders to the responsive neurostimulator system.

, 2023
How responsive neurostimulation (RNS) decreases seizure frequency is unclear. Stimulation may alter epileptic networks during inter-ictal epochs. Definitions of the epileptic network vary but fast ripples (FRs) may be an important substrate.
Wu, Chengyuan, MD, Engel, Jerome, Rubinstein, Daniel, Stern, John, Weiss, Shennan Aibel, Sperling, Michael R, Eliashiv, Dawn, Fried, Itzhak, Staba, Richard, Sharan, Ashwini   +9 more
core   +1 more source

Efficacy of Responsive Neurostimulation in Generalized Epilepsy: A Systematic Review

This protocol outlines the methodology for a systematic review investigating the efficacy of responsive neurostimulation (RNS) in generalized epilepsy. The review aims to synthesize current evidence on RNS applications in generalized epilepsy, addressing
Alaleh Alizadeh
core   +1 more source

Bilateral pulvinar responsive neurostimulation for bilateral multifocal posteriorly dominant drug resistant epilepsy

Epilepsia Open
Objective To describe four cases of Responsive Neurostimulation (RNS) in the bilateral pulvinar nuclei (PUL) in individuals with drug resistant epilepsy (DRE). This will show that due to widespread PUL connectivity, bilateral PUL RNS may be an option for
Richard Wang, Ariel Sacknovitz, Sima Vazquez, Jose Dominguez, Patty McGoldrick, Steven Wolf, Vishad Sukul, Carrie Muh, Sanjay E. Patra, David E. Burdette   +9 more
doaj   +1 more source

Predictive Biomarkers for Responsive Neurostimulation in Drug-Resistant Epilepsy: A Systematic Review

This is a protocol for a systematic review examining predictive biomarkers for responsive neurostimulation (RNS) efficacy in drug-resistant epilepsy.
Alaleh Alizadeh
core   +1 more source

Laser amygdalohippocampotomy reduces contralateral hippocampal sub-clinical activity in bitemporal epilepsy: A case illustration of responsive neurostimulator ambulatory recordings

Epilepsy & Behavior Reports
Responsive neurostimulation (RNS) is a valuable tool in the diagnosis and treatment of medication refractory epilepsy (MRE) and provides clinicians with better insights into patients’ seizure patterns. In this case illustration, we present a patient with
Hael F. Abdulrazeq, Anna R. Kimata, Belinda Shao, Konstantina Svokos, Neishay Ayub, Duyu Nie, Wael F. Asaad   +6 more
doaj   +1 more source