Insights into Reston virus spillovers and adaption from virus whole genome sequences. [PDF]
PLoS ONE, 2017 Reston virus (family Filoviridae) is unique among the viruses of the Ebolavirus genus in that it is considered non-pathogenic in humans, in contrast to the other members which are highly virulent.
César G Albariño +6 more
doaj +5 more sources
Risk assessment of Ebola Reston virus in humans in the Philippines [PDF]
Western Pacific Surveillance and Response, 2019 Objective: There have been five documented outbreaks of Ebola Reston virus (RESTV) in animals epidemiologically linked to the Philippines. This assessment was conducted to determine the risk of RESTV occurring in humans in the Philippines and its ...
Johnette A Peñas +4 more
doaj +5 more sources
Differences in Viral RNA Synthesis but Not Budding or Entry Contribute to the In Vitro Attenuation of Reston Virus Compared to Ebola Virus [PDF]
Microorganisms, 2020 Most filoviruses cause severe disease in humans. For example, Ebola virus (EBOV) is responsible for the two most extensive outbreaks of filovirus disease to date, with case fatality rates of 66% and 40%, respectively. In contrast, Reston virus (RESTV) is
Bianca S. Bodmer +7 more
doaj +5 more sources
Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines [PDF]
BMC Veterinary Research, 2012 Background Ebolaviruses induce lethal viral hemorrhagic fevers (VHFs) in humans and non-human primates, with the exceptions of Reston virus (RESTV), which is not pathogenic for humans.
Taniguchi Satoshi +14 more
doaj +5 more sources
Molecular evidence of Ebola Reston virus infection in Philippine bats. [PDF]
Virol J, 2015 In 2008-09, evidence of Reston ebolavirus (RESTV) infection was found in domestic pigs and pig workers in the Philippines. With species of bats having been shown to be the cryptic reservoir of filoviruses elsewhere, the Philippine government, in conjunction with the Food and Agriculture Organization of the United Nations, assembled a multi-disciplinary
Jayme SI +20 more
europepmc +6 more sources
Domestic pigs are susceptible to experimental infection with non-human primate-derived Reston virus without the need for adaptation [PDF]
Scientific Reports, 2023 Domestic pigs are a critical component of the food supply and one of the most commonly raised production animals. Pork consumption has driven the intensification of pig production expanding into environments conducive to increased emergence and spread of
Charles E. Lewis +7 more
doaj +4 more sources
Geographic Disparities in Domestic Pig Population Exposure to Ebola Viruses, Guinea, 2017–2019 [PDF]
Emerging Infectious DiseasesAlthough pigs are naturally susceptible to Reston virus and experimentally to Ebola virus (EBOV), their role in Orthoebolavirus ecology remains unknown.
Solène Grayo +10 more
doaj +2 more sources
Risks Posed by Reston, the Forgotten Ebolavirus [PDF]
mSphere, 2016 Out of the five members of the Ebolavirus family, four cause life-threatening disease, whereas the fifth, Reston virus (RESTV), is nonpathogenic in humans. The reasons for this discrepancy remain unclear.
Diego Cantoni +4 more
doaj +4 more sources
Ebolavirus replication and Tetherin/BST-2 [PDF]
Frontiers in Microbiology, 2012 Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro eYasuda
doaj +3 more sources
Non-Ebola Filoviruses: Potential Threats to Global Health Security [PDF]
VirusesFiloviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama +2 more
doaj +2 more sources