A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES [PDF]
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
doaj +2 more sources
Epidemiology of Ebola (Subtype Reston) Virus in the Philippines, 1996 [PDF]
Journal of Infectious Diseases, 1999 (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Ali S Khan +2 more
exaly +4 more sources
Virology, 2005 The only known filovirus, which presumably is not pathogenic for humans, is Ebola virus (EBOV) Reston. When EBOV Reston and the highly pathogenic EBOV Zaire were grown in cell culture, comparison of the replication kinetics showed a clear growth impairment of EBOV Reston, indicating that the replication cycle of EBOV Reston might be delayed.
Elke Műhlberger, Sven Enterlein
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Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain [PDF]
Journal of Molecular Biology, 2010 Ebolaviruses are causative agents of lethal hemorrhagic fever in humans and nonhuman primates. Among the filoviruses characterized thus far, Reston Ebola virus (REBOV) is the only Ebola virus that is nonpathogenic to humans despite the fact that REBOV can cause lethal disease in nonhuman primates.
Gaya Amarasinghe +2 more
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Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species [PDF]
Structure, 2019 The multifunctional virion protein 35 (VP35) of ebolaviruses is a critical determinant of virulence and pathogenesis indispensable for viral replication and host innate immune evasion. Essential for VP35 function is homo-oligomerization via a coiled-coil motif.
Luca Zinzula +2 more
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Geographic Disparities in Domestic Pig Population Exposure to Ebola Viruses, Guinea, 2017–2019 [PDF]
Emerging Infectious DiseasesAlthough pigs are naturally susceptible to Reston virus and experimentally to Ebola virus (EBOV), their role in Orthoebolavirus ecology remains unknown.
Solène Grayo +10 more
doaj +2 more sources
Development of an Immunofluorescence Method for the Detection of Antibodies to Ebola Virus Subtype Reston by the Use of Recombinant Nucleoprotein‐Expressing HeLa Cells [PDF]
Microbiology and Immunology, 2002 AbstractAn indirect immunofluorescent assay (IFA) to detect Ebola virus subtype Reston (EBO‐R) antibodies was developed by the use of a HeLa cell line stably expressing EBO‐R nucleoprotein (NP). This IFA has a high specificity for the detection of EBO‐R IgG antibodies in both hyperimmune rabbit sera and monkey sera collected during an EBO‐R outbreak in
Masayuki Saijo +2 more
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Risks Posed by Reston, the Forgotten Ebolavirus
mSphere, 2016 Out of the five members of the Ebolavirus family, four cause life-threatening disease, whereas the fifth, Reston virus (RESTV), is nonpathogenic in humans. The reasons for this discrepancy remain unclear.
Diego Cantoni +4 more
doaj +3 more sources
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan. [PDF]
Pharmacol Res PerspectABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Akinbolade S +5 more
europepmc +2 more sources
Animal DiseasesWe report the development of a triplex nucleic acid lateral flow immunoassay (NALFIA) for the detection of the genomes of Nipah virus (NiV), Middle East respiratory syndrome coronavirus (MERS-CoV) and Reston ebolavirus (REBOV), which are intended for ...
Santhalembi Chingtham +6 more
doaj +2 more sources