Differences in Viral RNA Synthesis but Not Budding or Entry Contribute to the In Vitro Attenuation of Reston Virus Compared to Ebola Virus [PDF]
Microorganisms, 2020 Most filoviruses cause severe disease in humans. For example, Ebola virus (EBOV) is responsible for the two most extensive outbreaks of filovirus disease to date, with case fatality rates of 66% and 40%, respectively. In contrast, Reston virus (RESTV) is
Bianca S. Bodmer +7 more
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Insights into Reston virus spillovers and adaption from virus whole genome sequences. [PDF]
PLoS ONE, 2017 Reston virus (family Filoviridae) is unique among the viruses of the Ebolavirus genus in that it is considered non-pathogenic in humans, in contrast to the other members which are highly virulent.
César G Albariño +6 more
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Risk assessment of Ebola Reston virus in humans in the Philippines [PDF]
Western Pacific Surveillance and Response, 2019 Objective: There have been five documented outbreaks of Ebola Reston virus (RESTV) in animals epidemiologically linked to the Philippines. This assessment was conducted to determine the risk of RESTV occurring in humans in the Philippines and its ...
Johnette A Peñas +4 more
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Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines [PDF]
BMC Veterinary Research, 2012 Background Ebolaviruses induce lethal viral hemorrhagic fevers (VHFs) in humans and non-human primates, with the exceptions of Reston virus (RESTV), which is not pathogenic for humans.
Taniguchi Satoshi +14 more
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Domestic pigs are susceptible to experimental infection with non-human primate-derived Reston virus without the need for adaptation [PDF]
Scientific ReportsDomestic pigs are a critical component of the food supply and one of the most commonly raised production animals. Pork consumption has driven the intensification of pig production expanding into environments conducive to increased emergence and spread of
Charles E. Lewis +7 more
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Reston Virus Causes Severe Respiratory Disease in Young Domestic Pigs [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2021 Juergen A. Richt +2 more
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Filovirus reactive antibodies in wildlife hunting communities suggest ongoing zoonotic spillover in forested Guinea [PDF]
Nature CommunicationsForested Guinea has been the site of multiple high-consequence viral spillover events, including the index case of the 2013-16 West African Ebola epidemic.
Grace Hood +17 more
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Frontiers in Virology, 2022 Uveitis is a common manifestation of post-Ebola syndrome, associated with persistence of Ebola virus (EBOV; Zaire ebolavirus) inside the eye. The iris and retinal pigment epithelia are key components of the blood-ocular barriers, but have the capacity to
Shawn Todd +8 more
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One-Step Reverse-Transcription FRET-PCR for Differential Detection of Five Ebolavirus Species. [PDF]
PLoS ONE, 2015 Ebola is an emerging infectious disease caused by a deadly virus belonging to the family Filoviridae, genus Ebolavirus. Based on their geographical distribution, Ebolavirus has been classified into total five species so far, mainly Zaire, Sudan, Taï ...
Guangwu Lu +6 more
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Serological evidence of Ebola virus infection in Indonesian orangutans. [PDF]
PLoS ONE, 2012 Ebola virus (EBOV) and Marburg virus (MARV) belong to the family Filoviridae and cause severe hemorrhagic fever in humans and nonhuman primates. Despite the discovery of EBOV (Reston virus) in nonhuman primates and domestic pigs in the Philippines and ...
Chairul A Nidom +11 more
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