Results 91 to 100 of about 7,824 (204)

Ebola virus disease: past, present and future

Asian Pacific Journal of Tropical Biomedicine, 2015
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak, Deepak Kumar Jain, Avineesh Singh, Ajay Kumar Sharma, Anshuman Dixit   +4 more
doaj   +1 more source

Identification of a small molecule inhibitor of Ebolavirus genome replication and transcription using in silico screening. [PDF]

, 2018
Ebola virus (EBOV) causes a severe haemorrhagic fever in humans and has a mortality rate over 50%. With no licensed drug treatments available, EBOV poses a significant threat.
Barr, JN, Easton, V, Edwards, TA, Fishwick, C, Foster, R, Garcia-Dorival, I, Harris, M, McPhillie, M   +7 more
core   +1 more source

Adult Neurogenesis and the Initiation of Social Aggression in Male Mice

Hippocampus, Volume 34, Issue 12, Page 711-728, December 2024.
ABSTRACT The hippocampus is important for social behavior and exhibits unusual structural plasticity in the form of continued production of new granule neurons throughout adulthood, but it is unclear how adult neurogenesis contributes to social interactions.
Mumeko C. Tsuda, Talia Akoh‐Arrey, Jeffrey C. Mercurio, Ariana Rucker, Megan L. Airey, Hannah Jacobs, Daria Lukasz, Lijing Wang, Heather A. Cameron   +8 more
wiley   +1 more source

Virus Ebola-Reston. ¿el cerdo, un nuevo hospedador? [PDF]

Ebola-Reston is species of the Ebola virus that was identified for the first time in 1989 in the United States. Several outbreaks have happened since then, affecting monkeys and humans in contact with these, without producing any disease or death in the ...
Martínez-lópez, Beatriz, Mur Gil, Lina, Sánchez-vizcaíno, Jose Manuel   +2 more
core   +1 more source

Histopathology of Natural Ebola Virus Subtype Reston Infection in Cynomolgus Macaques during the Philippine Outbreak in 1996.

Experimental Animals, 2002
We investigated the livers, spleens, kidneys and lungs collected from 24 cynomolgus macaques (Macaca fascicularis) naturally infected with Ebola virus subtype Reston (EBO-R) during the Philippine outbreak in 1996, in order to reveal the histopathologic findings.
Tetsuro, Ikegami, Mary Elizabeth G, Miranda, Alan B, Calaor, Daria L, Manalo, Noel J, Miranda, Masahiro, Niikura, Masayuki, Saijo, Yumi, Une, Yasuo, Nomura, Ichiro, Kurane, Thomas G, Ksiazek, Yasuhiro, Yoshikawa, Shigeru, Morikawa   +12 more
openaire   +3 more sources

A public, cross‐reactive glycoprotein epitope confounds Ebola virus serology

Journal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in treating cases despite promising therapeutic development, EBOD is a high priority in public health research.
Markus H. Kainulainen, Jessica R. Harmon, Elif Karaaslan, Jackson Kyondo, Amy Whitesell, Sam Twongyeirwe, Jason H. Malenfant, Jimmy Baluku, Aaron Kofman, Éric Bergeron, Michelle A. Waltenburg, Luke Nyakarahuka, Stephen Balinandi, Caitlin M. Cossaboom, Mary J. Choi, Trevor R. Shoemaker, Joel M. Montgomery, Christina F. Spiropoulou   +17 more
wiley   +1 more source

Fruit–frugivore dependencies are important in Ebolavirus outbreaks in Sub‐Saharan Africa

Ecography, Volume 2024, Issue 10, October 2024.
Ebolaviruses have the ability to infect a wide variety of species, with many African mammals potentially serving either as primary reservoirs or secondary amplifying hosts. Previous work has shown that frugivorous bats and primates are often associated with spillover and outbreaks.
Mekala Sundaram, Mireya Dorado, Benedicta Akaribo, Antoine Filion, Barbara A. Han, Nicole L. Gottdenker, John P. Schmidt, John M. Drake, Patrick R. Stephens   +8 more
wiley   +1 more source

Elevated reactive aggression in forebrain‐specific Ccn2 knockout mice

Journal of Cell Communication and Signaling, Volume 18, Issue 3, September 2024.
Cellular communication network factor 2 (CCN2) is expressed in the olfactory bulb, anterior olfactory nucleus, frontal cortex (FC), and cortical layer IVb. Intruder mice elicit greater neuronal signals in the medial amygdala, in mice lacking CCN2, resulting in greater reactive aggression during resident‐intruder task.
Ho‐Ching Chang, Chi‐Hou Ng, Yu‐Fu Chen, Yu‐Chun Wang, I‐Shing Yu, Lukas Jyuhn‐Hsiarn Lee, Li‐Jen Lee, Kuang‐Yung Lee   +7 more
wiley   +1 more source

Meat production and zoonotic disease outbreaks in Asia

Australian Journal of Agricultural and Resource Economics, Volume 68, Issue 3, Page 567-586, July 2024.
Abstract Is there a link between meat production and infectious diseases? Researchers, policymakers and pundits argue that the growth of demand for meat in Asia can increase the risk of zoonotic diseases, pathogens that originate in animals and can be transmitted to humans. Using original data on zoonotic disease outbreaks in 22 Asian countries between
Ore Koren, Jessica Steinberg, Amit Hagar
wiley   +1 more source

Cathepsin B & L are not required for ebola virus replication.

PLoS Neglected Tropical Diseases, 2012
Ebola virus (EBOV), family Filoviridae, emerged in 1976 on the African continent. Since then it caused several outbreaks of viral hemorrhagic fever in humans with case fatality rates up to 90% and remains a serious Public Health concern and biothreat ...
Andrea Marzi, Thomas Reinheckel, Heinz Feldmann   +2 more
doaj   +1 more source