Results 71 to 80 of about 2,434 (146)

Ebola virus disease: past, present and future

Asian Pacific Journal of Tropical Biomedicine, 2015
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak, Deepak Kumar Jain, Avineesh Singh, Ajay Kumar Sharma, Anshuman Dixit   +4 more
doaj   +1 more source

MAGPIX Assay for Influenza A Using Single Domain Antibodies

Analysis &Sensing, Volume 5, Issue 2, March 2025.
Single domain antibodies (sdAbs) are small, stable recognition elements that can be engineered for specific applications. We incorporated sdAbs into a magnetic bead‐based immunoassay for the detection of influenza A and demonstrated performance with clinical samples. Using a bivalent format improved assay performance. Abstract Single domain antibodies (
Ellen R. Goldman, Victor A. Sugiharto, Lisa C. Shriver‐Lake, Andrew M. Garcia, Shuenn‐Jue Wu, Sarah A. Jenkins, Hua‐Wei Chen   +6 more
wiley   +1 more source

Non-Ebola Filoviruses: Potential Threats to Global Health Security

Viruses
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama, Francois Edidi-Atani, Ayato Takada   +2 more
doaj   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +2 more sources

Ebolavirus replication and Tetherin/BST-2

Frontiers in Microbiology, 2012
Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro eYasuda
doaj   +1 more source

Ebolavirus evolution and emergence are associated with land use change

Ecological Monographs, Volume 95, Issue 1, February 2025.
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange, Thomas R. Barnum, David J. McIver, Matthew LeBreton, Karen Saylors, Charles Kumakamba, Sara Lowes, Eduardo Montero, Robert L. Cohen   +8 more
wiley   +1 more source

Inter‐Reader Agreement for Contrast‐Enhanced Ultrasound Liver Imaging Reporting and Data System Major Features and Final Categorization

Journal of Ultrasound in Medicine, Volume 44, Issue 2, Page 349-357, February 2025.
Objectives Contrast‐enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI‐RADS) is used to definitively diagnose hepatocellular carcinoma (HCC) in patients at risk. However, the user variability associated with CEUS LI‐RADS has not been validated in North American and European patients.
Cristina M. Kuon Yeng Escalante, Tania Siu Xiao, Yuko Kono, Fabio Piscaglia, Stephanie R. Wilson, Alexandra Medellin, Shuchi K. Rodgers, Virginia Planz, Aya Kamaya, David T. Fetzer, Annalisa Berzigotti, Paul S. Sidhu, Corinne E. Wessner, Kristen Bradigan, John R. Eisenbrey, Flemming Forsberg, Andrej Lyshchik, CEUS LI‐RADS Trial Group, Gibran T. Yusuf, Abid Suddle, Vasileios D. Rafailidis, Lorenzo Mulazzani, Alessandro Granito, Eleonora Terzi, Antonella Forgione, Alice Giamperoli, Bernardo Stefanini, Iuliana‐Pompilia Radu, Amit G. Singal   +28 more
wiley   +1 more source

Histopathology of Natural Ebola Virus Subtype Reston Infection in Cynomolgus Macaques during the Philippine Outbreak in 1996.

Experimental Animals, 2002
We investigated the livers, spleens, kidneys and lungs collected from 24 cynomolgus macaques (Macaca fascicularis) naturally infected with Ebola virus subtype Reston (EBO-R) during the Philippine outbreak in 1996, in order to reveal the histopathologic findings.
IKEGAMI, Tetsuro, MIRANDA, Mary Elizabeth G, CALAOR, Alan B, MANALO, Daria L, MIRANDA, Noel J, NIIKURA, Masahiro, SAIJO, Masayuki, UNE, Yumi, NOMURA, Yasuo, KURANE, Ichiro, KSIAZEK, Thomas G, YOSHIKAWA, Yasuhiro, MORIKAWA, Shigeru   +12 more
openaire   +3 more sources

Genetically humanized phenylketonuria mouse model as a testing tool for human genome editing in fertilized eggs

Journal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.
Abstract Targeted genome editing has made significant advancements; however, safety and ethical issues have not been fully elucidated, resulting in strict control of the technique. We tested genome editing tools on gametes from a genetically humanized mouse model using a phenylketonuria (PKU) mouse model to gain insights into genome editing in human ...
Atsumi Tsuji‐Hosokawa, Iku Tsuchiya, Kie Shimizu, Miho Terao, Mito Yasuhara, Natsuho Miyamoto, Saki Kikuchi, Yuya Ogawa, Kazuaki Nakamura, Yoichi Matsubara, Shuji Takada   +10 more
wiley   +1 more source