Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi +6 more
wiley +1 more source
Postcard: Gulf Reston, Inc., "Reston, Virginia," Undated
Textual: postcard, original; 5.5" x 3.5" (14 cm x 8.9 cm)Postcard produced by Gulf Reston, Inc. entitled "Reston, Virginia" that is undated. This is a postcard of Lakeview Cluster in Reston, Virginia. Lakeview cluster is located on Lake Anne.
Gulf Reston, Inc.
core +1 more source
The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold. [PDF]
Ebolaviruses cause hemorrhagic fever with up to 90% lethality and in fatal cases, are characterized by early suppression of the host innate immune system. One of the proteins likely responsible for this effect is VP24.
Adrianna P P Zhang +7 more
doaj +1 more source
In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40
The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara +13 more
wiley +1 more source
Advertisement: Reston Land Corporation, "Reston Advertisements," Undated
Textual: advertisement, original; 11” x 8.5” (27.9 cm x 21.6 cm)Collection of advertisements from Reston Land Corporation that discuss Reston Virginia. These advertisements are undated.
Reston Land Corporation
core +1 more source
Genome sequence analyses of the 2014 Ebola Virus (EBOV) isolates revealed a potential problem with the diagnostic assays currently in use; i.e., drifting genomic profiles of the virus may affect the sensitivity or even produce false-negative results.
Shanmuga Sozhamannan +11 more
doaj +1 more source
Transcriptional analysis of viral mRNAs reveals common transcription patterns in cells infected by five different filoviruses. [PDF]
Filoviruses are notorious viral pathogens responsible for high-consequence diseases in humans and non-human primates. Transcription of filovirus mRNA shares several common features with transcription in other non-segmented negative-strand viruses ...
César G Albariño +3 more
doaj +1 more source
Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24
Members of the Ebolavirus genus demonstrate a marked differences in pathogenicity in humans with Ebola (EBOV) being the most pathogenic, Bundibugyo (BDBV) less pathogenic, and Reston (RESTV) is not known to cause a disease in humans.
Palaniappan Ramanathan +11 more
doaj +1 more source
Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley +1 more source
Newsletter: Reston Land Corporation, "Reston," Spring/Summer 1983
Textual: Newsletter, glossy paper; 11" x 8.5" (27.9 cm x 21.6 cm)Newsletter produced by the Reston Land Corporation entitled "Reston" from 1983. This newsletter is broken up into articles that cover various topics concerning Reston, Virginia.
Reston Land Corporation
core +1 more source

