Results 11 to 20 of about 7,824 (204)

A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES [PDF]

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova, V. N. Lebedev, N. V. Karulina, O. V. Chukhralya, S. I. Syromyatnikova, S. V. Borisevich   +5 more
doaj   +2 more sources

Reston virus causes severe respiratory disease in young domestic pigs. [PDF]

Proc Natl Acad Sci U S A, 2021
Significance The emergence of Reston virus (RESTV) in domestic pigs in the Philippines and, subsequently, the detection of RESTV sequences in pigs in China are serious human and animal health concerns. Food safety is an immediate fear, and pathogenicity and potential for zoonotic transmission are important concerns.
Haddock E, Saturday G, Feldmann F, Hanley PW, Okumura A, Lovaglio J, Long D, Thomas T, Scott DP, Pulliam M, Richt JA, de Wit E, Feldmann H.   +12 more
europepmc   +4 more sources

Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice. [PDF]

JCI Insight, 2019
Filoviruses of the genus Ebolavirus include 6 species with marked differences in their ability to cause disease in humans. From the highly virulent Ebola virus to the seemingly nonpathogenic Reston virus, case fatality rates can range between 0% and 90%.
Escudero-Pérez B, Ruibal P, Rottstegge M, Lüdtke A, Port JR, Hartmann K, Gómez-Medina S, Müller-Guhl J, Nelson EV, Krasemann S, Rodríguez E, Muñoz-Fontela C.   +11 more
europepmc   +4 more sources

Sequence of Reston Virus Isolate AZ-1435, an Ebolavirus Isolate Obtained during the 1989-1990 Reston Virus Epizootic in the United States. [PDF]

Genome Announc, 2017
ABSTRACT Reston virus (RESTV) was discovered in 1989–1990 during three connected epizootics of highly lethal viral hemorrhagic fever among captive macaques in primate housing facilities in the United States and Philippines. Currently, only one RESTV isolate from that outbreak (named Pennsylvania) has been sequenced.
Cornish JP, Diaz L, Ricklefs SM, Kanakabandi K, Sword J, Jahrling PB, Kuhn JH, Porcella SF, Johnson RF.   +8 more
europepmc   +4 more sources

Severity of Disease in Humanized Mice Infected With Ebola Virus or Reston Virus Is Associated With Magnitude of Early Viral Replication in Liver. [PDF]

J Infect Dis, 2017
Both Ebola virus (EBOV) and Reston virus (RESTV) cause disease in nonhuman primates, yet only EBOV causes disease in humans. To investigate differences in viral pathogenicity, humanized mice (hu-NSG-SGM3) were inoculated with EBOV or RESTV. Consistent with differences in disease in human infection, pronounced weight loss and markers of hepatic damage ...
Spengler JR, Saturday G, Lavender KJ, Martellaro C, Keck JG, Nichol ST, Spiropoulou CF, Feldmann H, Prescott J.   +8 more
europepmc   +5 more sources

Brief Research Report: Ebola Virus Differentially Infects Human Iris and Retinal Pigment Epithelial Cells

Frontiers in Virology, 2022
Uveitis is a common manifestation of post-Ebola syndrome, associated with persistence of Ebola virus (EBOV; Zaire ebolavirus) inside the eye. The iris and retinal pigment epithelia are key components of the blood-ocular barriers, but have the capacity to
Shawn Todd, Yuefang Ma, Liam M. Ashander, Binoy Appukuttan, Michael Z. Michael, Timothy A. Blenkinsop, Steven Yeh, Glenn A. Marsh, Justine R. Smith   +8 more
doaj   +1 more source

One-Step Reverse-Transcription FRET-PCR for Differential Detection of Five Ebolavirus Species. [PDF]

PLoS ONE, 2015
Ebola is an emerging infectious disease caused by a deadly virus belonging to the family Filoviridae, genus Ebolavirus. Based on their geographical distribution, Ebolavirus has been classified into total five species so far, mainly Zaire, Sudan, Taï ...
Guangwu Lu, Jilei Zhang, Chuntao Zhang, Xiaolu Li, Dawei Shi, Zhaopeng Yang, Chengming Wang   +6 more
doaj   +1 more source

Novel triplex nucleic acid lateral flow immunoassay for rapid detection of Nipah virus, Middle East respiratory syndrome coronavirus and Reston ebolavirus

Animal Diseases
We report the development of a triplex nucleic acid lateral flow immunoassay (NALFIA) for the detection of the genomes of Nipah virus (NiV), Middle East respiratory syndrome coronavirus (MERS-CoV) and Reston ebolavirus (REBOV), which are intended for ...
Santhalembi Chingtham, Diwakar D. Kulkarni, Sumi Sivaraman, Anamika Mishra, Atul K. Pateriya, Vijendra Pal Singh, Ashwin Ashok Raut   +6 more
doaj   +2 more sources

Serological evidence of Ebola virus infection in Indonesian orangutans. [PDF]

PLoS ONE, 2012
Ebola virus (EBOV) and Marburg virus (MARV) belong to the family Filoviridae and cause severe hemorrhagic fever in humans and nonhuman primates. Despite the discovery of EBOV (Reston virus) in nonhuman primates and domestic pigs in the Philippines and ...
Chairul A Nidom, Eri Nakayama, Reviany V Nidom, Mohamad Y Alamudi, Syafril Daulay, Indi N L P Dharmayanti, Yoes P Dachlan, Mohamad Amin, Manabu Igarashi, Hiroko Miyamoto, Reiko Yoshida, Ayato Takada   +11 more
doaj   +1 more source

Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity

Virulence, 2021
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj   +1 more source