Results 31 to 40 of about 7,824 (204)

Ébola, lo que debemos saber

Revista Ciencias Biomédicas, 2020
La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
doaj   +1 more source

Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]

, 2000
The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M, Borchert, M, Colebunders, R, Muyembe-Tamfum, J J, Pirard, P, Sleurs, H, van der Groen, G, Van der Stuyft, P   +7 more
core   +3 more sources

Investigating the Cellular Transcriptomic Response Induced by the Makona Variant of Ebola Virus in Differentiated THP-1 Cells

Viruses, 2019
Recent studies have shown that transcriptomic analysis of blood samples taken from patients with acute Ebola virus disease (EVD) during the 2013−2016 West African outbreak was suggestive that a severe inflammatory response took place in acutely ill
Andrew Bosworth, Stuart D. Dowall, Stuart Armstrong, Xuan Liu, Xiaofeng Dong, Christine B. Bruce, Lisa F. P. Ng, Miles W. Carroll, Roger Hewson, Julian A. Hiscox   +9 more
doaj   +1 more source

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. [PDF]

PLoS Pathogens, 2015
The filoviruses, which include the marburg- and ebolaviruses, have caused multiple outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein (GP) have been shown to provide life-saving therapy in nonhuman primates, but ...
Marnie L Fusco, Takao Hashiguchi, Robyn Cassan, Julia E Biggins, Charles D Murin, Kelly L Warfield, Sheng Li, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Gene G Olinger, Do H Kim, Kevin J Whaley, Larry Zeitlin, Andrew B Ward, Cory Nykiforuk, M Javad Aman, Jody D Berry, Erica Ollmann Saphire   +18 more
doaj   +1 more source

Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain [PDF]

Journal of Molecular Biology, 2010
Ebolaviruses are causative agents of lethal hemorrhagic fever in humans and nonhuman primates. Among the filoviruses characterized thus far, Reston Ebola virus (REBOV) is the only Ebola virus that is nonpathogenic to humans despite the fact that REBOV can cause lethal disease in nonhuman primates.
Daisy W, Leung, Reed S, Shabman, Mina, Farahbakhsh, Kathleen C, Prins, Dominika M, Borek, Tianjiao, Wang, Elke, Mühlberger, Christopher F, Basler, Gaya K, Amarasinghe   +8 more
openaire   +2 more sources

Ebola hemorrhagic fever outbreaks: strategies for effective epidemic management, containment and control

Brazilian Journal of Infectious Diseases, 2015
Ebola hemorrhagic fever, caused by the highly virulent RNA virus of the filoviridae family, has become one of the world's most feared pathogens. The virus induces acute fever and death, often associated with hemorrhagic symptoms in up to 90% of infected ...
Gerald Amandu Matua, Dirk Mostert Van der Wal, Rozzano C. Locsin   +2 more
doaj   +1 more source

In vivo characterization of the novel ebolavirus Bombali virus suggests a low pathogenic potential for humans

Emerging Microbes and Infections, 2023
Ebolaviruses cause outbreaks of haemorrhagic fever in Central and West Africa. Some members of this genus such as Ebola virus (EBOV) are highly pathogenic, with case fatality rates of up to 90%, whereas others such as Reston virus (RESTV) are apathogenic
B. S. Bodmer, A. Breithaupt, M. Heung, J. E. Brunetti, C. Henkel, J. Müller-Guhl, E. Rodríguez, L. Wendt, S. L. Winter, M. Vallbracht, A. Müller, S. Römer, P. Chlanda, C. Muñoz-Fontela, T. Hoenen, B. Escudero-Pérez   +15 more
doaj   +1 more source

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]

, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla, A MacNeil, A Tuffs, AJ Georges, AM Casillas, B Jeffs, B Le Guenno, Benjamin Jeffs, BS Hewlett, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DH Smith, DL Heymann, E Mupere, ED Johnson, EM Leroy, EM Leroy, Esther Sterk, GA Martini, GA Martini, JL Conrad, Joseph Wamala, JS Gear, JS Towner, Julius Lutwama, K Kibadi, K Mupapa, K Mupapa, KJ Davis, M Borchert, M Bray, M Bray, MA Bwaka, Malcolm Gracie Semple, Maria D. Van Kerkhove, Matthias Borchert, ME Miranda, Michel Van Herp, MJ Bonnet, Natasha Howard, NK Jaax, P Formenty, P Formenty, P Francesconi, P Roddy, P Roddy, Paul Roddy, PE Rollin, Pedro Pablo Palma, PH Sureau, R Colebunders, R Ndambi, R Siegert, RC Baron, Robert Colebunders, RT Emond, S Becker, SF Dowell, SP Fisher-Hoch, SR Zaki, TH Roels, U Stroher, Y Kalongi, Zabulon Yoti   +66 more
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Species-specific quantification of circulating ebolavirus burden using VP40-derived peptide variants.

PLoS Pathogens, 2021
Six ebolavirus species are reported to date, including human pathogens Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV); non-human pathogen Reston virus (RESTV); and the plausible Bombali virus (BOMV).
Qingbo Shu, Tara Kenny, Jia Fan, Christopher J Lyon, Lisa H Cazares, Tony Y Hu   +5 more
doaj   +3 more sources

Analysis of the role of predicted RNA secondary structures in Ebola virus replication [PDF]

, 1949
Thermodynamic modeling of Ebola viral RNA predicts the formation of RNA stem-loop structures at the 3′ and 5′ termini and panhandle structures between the termini of the genomic (or antigenomic) RNAs.
Crary, Sharon M, Towner, Jonathan S, Honig, Jessica E, Shoemaker, Trevor R, Nichol, Stuart T   +4 more
core   +1 more source