Results 71 to 80 of about 7,824 (204)

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24

open access: yesViruses, 2023
Members of the Ebolavirus genus demonstrate a marked differences in pathogenicity in humans with Ebola (EBOV) being the most pathogenic, Bundibugyo (BDBV) less pathogenic, and Reston (RESTV) is not known to cause a disease in humans.
Palaniappan Ramanathan   +11 more
doaj   +1 more source

Ebola : too far or so close? [PDF]

open access: yes, 2014
The year 2014 has witnessed the escalation of the largest ever Ebola outbreak which started in Guinea, and later spread to other countries in West Africa.
Pace, David, Torpiano, Paul
core  

Marburg Virus Disease: A Narrative Review

open access: yesHealth Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati   +4 more
wiley   +1 more source

Novel functional hepatitis C virus glycoprotein isolates identified using an optimised viral pseudotype entry assay [PDF]

open access: yes, 2016
Retrovirus pseudotypes are a highly tractable model used to study the entry pathways of enveloped viruses. This model has been extensively applied to the study of the hepatitis C virus (HCV) entry pathway, pre-clinical screening of antiviral antibodies ...
Alexander W. Tarr   +7 more
core   +1 more source

Effect of in vivo reprogramming of astrocytes combined with exercise training on neurorepair in rats with spinal cord injury

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 4, Page 595-605, April 2025.
Exercise and astrocyte reprogramming synergize to enhance motor function and reduce glial scarring after spinal cord injury, with combined therapies surpassing individual effects. Abstract Background The inability of damaged neurons to regenerate and of axons to establish new functional connections leads to permanent functional deficits after spinal ...
Zuliyaer Talifu   +14 more
wiley   +1 more source

Evaluation of Signature Erosion in Ebola Virus Due to Genomic Drift and Its Impact on the Performance of Diagnostic Assays

open access: yesViruses, 2015
Genome sequence analyses of the 2014 Ebola Virus (EBOV) isolates revealed a potential problem with the diagnostic assays currently in use; i.e., drifting genomic profiles of the virus may affect the sensitivity or even produce false-negative results.
Shanmuga Sozhamannan   +11 more
doaj   +1 more source

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo. [PDF]

open access: yesPLoS Pathogens, 2012
Among the Ebola viruses most species cause severe hemorrhagic fever in humans; however, Reston ebolavirus (REBOV) has not been associated with human disease despite numerous documented infections.
Allison Groseth   +7 more
doaj   +1 more source

The Ebola outbreak, 2013-2016: old lessons for new epidemics [PDF]

open access: yes, 2017
Ebola virus causes a severe haemorrhagic fever in humans with high case fatality and significant epidemic potential. The 2013–2016 outbreak in West Africa was unprecedented in scale, being larger than all previous outbreaks combined, with 28 646 reported
Coltart, CEM   +4 more
core   +1 more source

MAGPIX Assay for Influenza A Using Single Domain Antibodies

open access: yesAnalysis &Sensing, Volume 5, Issue 2, March 2025.
Single domain antibodies (sdAbs) are small, stable recognition elements that can be engineered for specific applications. We incorporated sdAbs into a magnetic bead‐based immunoassay for the detection of influenza A and demonstrated performance with clinical samples. Using a bivalent format improved assay performance. Abstract Single domain antibodies (
Ellen R. Goldman   +6 more
wiley   +1 more source

Ebolavirus diagnosis made simple, comparable and faster than molecular detection methods: preparing for the future

open access: yesVirology Journal, 2018
Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James   +4 more
doaj   +1 more source

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