Results 171 to 180 of about 268,348 (303)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Functional Analysis of MmeI from Methanol UtilizerMethylophilus methylotrophus, a Subtype IIC Restriction-Modification Enzyme Related to Type I Enzymes

, 2008
Joanna Nakonieczna, Tadeusz Kaczorowski, Agnieszka Obarska-Kosińska, Janusz M. Bujnicki   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Restriction Enzyme [PDF]

, 2019
openaire   +2 more sources

Increasing Genome Sampling and Improving SNP Genotyping for Genotyping-by-Sequencing with New Combinations of Restriction Enzymes. [PDF]

G3 (Bethesda), 2016
Fu YB, Peterson GW, Dong Y.
europepmc   +1 more source

Protein profiling and restriction enzyme analysis of Riemerella anatipestifer from ducks in Kerala

, 2016
P.S. Surya, P.M. Priya, M. Mini
openalex   +1 more source

Rapid Screening for Penicillin Susceptibility of Systemic Pneumococcal Isolates by Restriction Enzyme Profiling of the pbp2B Gene [PDF]

, 1998
Bernard Beall, Richard R. Facklam, Delois Jackson, Holly H. Starling   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Restriction Enzyme Generated Next-Generation Sequencing Libraries and Genetic Risk Modifiers of BRCA1 Mutation Carriers

, 2016
Bradley M. Downs
openalex   +1 more source

DNA recognition by a new family of type I restriction enzymes: a unique relationship between two different DNA specificities. [PDF]

, 1987
C P Price, James C. Shepherd, Thomas A. Bickle   +2 more
openalex   +1 more source