Results 171 to 180 of about 2,915,798 (345)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Using nucleolytic toxins as restriction enzymes enables new RNA applications. [PDF]

Nucleic Acids Res
Rothweiler U, Gundesø SE, Mikalsen EW, Svenning S, Singh M, Combes F, Pettersson FJ, Mangold A, Piotrowski Y, Schwab F, Lanes O, Striberny BK.   +11 more
europepmc   +1 more source

Restriction Enzymes as a Target for DNA-Based Sensing and Structural Rearrangement. [PDF]

ACS Omega, 2018
Buckhout-White S, Person C, Medintz IL, Goldman ER.   +3 more
europepmc   +1 more source

Rapid characterization of avian reoviruses using phylogenetic analysis, reverse transcription-polymerase chain reaction and restriction enzyme fragment length polymorphism [PDF]

, 2004
Hung‐Jen Liu, Long H. Lee, Wen L. Shih, Ying J. Li, Hung Y. Su   +4 more
openalex   +1 more source

Characterization of microbial diversity by determining terminal restriction fragment length polymorphisms of genes encoding 16S rRNA

Applied and Environmental Microbiology, 1997
Wen Tso Liu, T. Marsh, Hans H. Cheng, L. Forney   +3 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

An enterococcal phage protein inhibits type IV restriction enzymes involved in antiphage defense. [PDF]

Nat Commun
Bullen NP, Johnson CN, Andersen SE, Arya G, Marotta SR, Lee YJ, Weigele PR, Whitney JC, Duerkop BA.   +8 more
europepmc   +1 more source

Determining if DNA Stained with a Cyanine Dye Can Be Digested with Restriction Enzymes. [PDF]

J Vis Exp, 2018
Maschmann A, Masters C, Davison M, Lallman J, Thompson D, Kounovsky-Shafer KL.   +5 more
europepmc   +1 more source

Rapid detection and characterization of foot-and-mouth disease virus by restriction enzyme and nucleotide sequence analysis of PCR products [PDF]

, 1995
Franziska Locher, V. V. S. Suryanarayana, Jon Duri Tratschin   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source