Results 71 to 80 of about 3,130,340 (386)

Molecular characterization of Salmonella Enteritidis : comparison of an optimized multi-locus variable-number of tandem repeat analysis (MLVA) and pulsed-field gel electrophoresis [PDF]

, 2012
Salmonella Enteritidis (SE) is a genetically homogenous serovar, which makes optimal subtype discrimination crucial for epidemiological research. This study describes the development and evaluation of an optimized multiple-locus variable number tandem ...
Bertrand, Sophie, De Reu, Koen, Dewaele, Isabelle, Ducatelle, Richard, Herman, Lieve, Heyndrickx, Marc, Imberechts, Hein, Rasschaert, Geertrui, Wattiau, Pierre, Wildemauwe, Christa   +9 more
core   +2 more sources

REBASE: restriction enzymes and methyltransferases [PDF]

Nucleic Acids Research, 2003
REBASE contains comprehensive information about restriction enzymes, DNA methyltransferases and related proteins such as nicking enzymes, specificity subunits and control proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data. Homing endonucleases are
Richard J, Roberts, Tamas, Vincze, Janos, Posfai, Dana, Macelis   +3 more
openaire   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Comparative analysis of 18S rRNA genes from Myxobolus aeglefini Auerbach, 1906 isolated from cod (Gadus morhua), Plaice (Pleuronectes platessa) and dab (Limanda limanda), using PCR-RFLP [PDF]

, 2002
The myxosporean parasite Myxobolus aeglefini is a marine species, which can be found in the cartilage of mainly gadid fish species. The parasite has, however, been recorded in the flatfish plaice (Pleuronectes platessa) and dab (Limanda limanda).
Buchmann, K., Koie, M., Nielsen, C. V., Székely, Csaba   +3 more
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Genomic-based restriction enzyme selection for specific detection of Piscirickettsia salmonis by 16S rDNA PCR-RFLP

Frontiers in Microbiology, 2016
The gram negative facultative bacterium P. salmonis is the etiological agent of Salmonid Rickettsial Septicaemia (SRS), a severe disease that causes important economic losses in the global salmon farmer industry.
Dinka eMandakovic, Dinka eMandakovic, Benjamín eGlasner, Jonathan eMaldonado, Jonathan eMaldonado, Pamela eAravena, Pamela eAravena, Mauricio eGonzalez, Mauricio eGonzalez, Mauricio eGonzalez, Verónica eCambiazo, Verónica eCambiazo, Verónica eCambiazo, Rodrigo ePulgar, Rodrigo ePulgar, Rodrigo ePulgar   +15 more
doaj   +1 more source

A novel zinc-finger nuclease platform with a sequence-specific cleavage module [PDF]

, 2011
Zinc-finger nucleases (ZFNs) typically consist of three to four zinc fingers (ZFs) and the non-specific DNA-cleavage domain of the restriction endonuclease FokI.
Cathomen, Toni, Dannemann, Nadine, Gabsalilow, Lilia, Pingoud, Alfred, Schierling, Benno, Wende, Wolfgang   +5 more
core   +2 more sources

Sequence-specific cleavage of RNA by Type II restriction enzymes

Nucleic Acids Research, 2010
The ability of 223 Type II restriction endonucleases to hydrolyze RNA–DNA heteroduplex oligonucleotide substrates was assessed. Despite the significant topological and sequence asymmetry introduced when one strand of a DNA duplex is substituted by RNA we
I. Murray, S. Stickel, R. Roberts
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Diversidade genética de Begomovirus que infectam plantas invasoras na região nordeste Genetic diversity of Begomovirus infecting weeds in northeastern Brazil

Planta Daninha, 2006
Os Begomovirus fazem parte de uma família numerosa de fitovírus denominada Geminiviridae. Eles infectam ampla gama de hospedeiras, incluindo muitas espécies cultivadas, como tomate (Lycopersicon esculentum), feijão (Phaseolus vulgaris), pimentão ...
I.P. Asssunção, A.F. Listik, M.C.S. Barros, E.P.R. Amorin, S.J.C. Silva, Izael O. Silva, C.E. Ramalho-Neto, G.S.A. Lima   +7 more
doaj   +1 more source