Results 91 to 100 of about 1,137,892 (286)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Revista Mexicana de Biodiversidad, 2010 Las secuencias génicas han contribuido enormemente a los estudios filogenéticos en plantas. Sin embargo, una desventaja importante en las secuencias de varios loci es su baja resolución filogenética para resolver las relaciones de taxa cercanamente ...
Dolores González
doaj
Epigenetics ReportsDNA base modifications influence genome function in both prokaryotes and eukaryotes, yet their detection often relies on specialised and resource-intensive technologies.
QingTao Zhang +7 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Two novel restriction enzymes from Campylobacter jejuni
, 2011 We have discovered two unusual restriction endonuclease (ENases) in two Campylobacter jejuni strains that recognize asymmetrical, interrupted sequences and cleave the DNA both before and after their recognition sites.
Morgan, Richard D., Vítor, Jorge M. B.
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Restriction enzymes and primers used for Inverse PCR.
, 2012 Restriction enzymes and primers used for Inverse PCR.
Sean P. Gordon (134614) +7 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Detailed information on the plasmids and restriction enzymes.
, 2013 Detailed information on the plasmids and restriction enzymes.
Sebastián Escobar (436316) +9 more
core +1 more source