Results 31 to 40 of about 2,919,054 (308)

A cost effective RFLP method to genotype Solute carrier organic anion 1B1 (SLCO1B1) c.1929A>C (p.Leu643Phe, rs34671512); a variant with potential effect on rosuvastatin pharmacokinetics

open access: yesBMC Research Notes, 2018
Objective This study describes a restriction fragment polymorphism protocol for rapidly screening the polymorphism SLCO1B1 c.1929A>C in genomic DNA samples.
Nyarai D. Soko   +2 more
doaj   +1 more source

Restriction Fragment Length Polymorphisms in Poultry Breeding

open access: yesPoultry Science, 1986
Abstract Restriction fragment length polymorphisms (RFLP) are a new class of genetic marker uncovered by means of recombinant deoxyribonucleic acid (DNA) methodologies. The RELP are formed as a result of point mutations or changes in chromosome structure that affect the distribution of restriction enzyme sites in the vicinity of a cloned gene used as
Soller, M., Beckmann, J. S.
openaire   +2 more sources

Agarose gel electrophoresis for restriction fragment length polymorphism of VDR Taq I.

open access: yes, 2018
Agarose gel electrophoresis for restriction fragment length polymorphism of VDR Taq I.
Hemantha Peiris (3482171)   +3 more
core   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

open access: yesAdvanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad   +12 more
wiley   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

IDENTIFICATION OF GRAM-NEGATIVE BACTERIA OF FISH BY THE METHOD OF PCR-RFLP OF 16S rDNA GENE

open access: yesRibogospodarsʹka Nauka Ukraïni, 2013
The complex method of polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) targeting to the 16S rDNA gene was developed for identification of the most widespread gram-negative bacterias of fish. The specificity and efficiency
Yu. Rud
doaj   +1 more source

Restriction fragment length polymorphism in Oryza sativa L.

open access: yes, 1989
Seventy varieties of rice, representing the breadth of the species Oryza sativa, were assayed with 10 rice restriction fragment length polymorphism markers.
Z. Y. Wang, S. D. Tanksley
core   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

open access: yesAdvanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su   +13 more
wiley   +1 more source

Restriction fragment length polymorphism among Israeli Holstein‐Friesian dairy bulls*

open access: yes, 1986
Israeli Holstein-Friesian dairy bulls were screened for restriction fragment length polymorphisms by hybridizing cloned DNA probes for bovine growth hormone, for chymosin, and for rat muscle beta-actin to restriction endonuclease-digested DNA immobilized
Y. KASHI   +9 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

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