Results 101 to 110 of about 94,066 (297)

Firm‐Level Climate Risk and Stock Price Crash: Does Investor Attention or Sentiment Matter?

Business Strategy and the Environment, EarlyView.
ABSTRACT This study moves beyond traditional crash‐risk channels focused on managerial bad‐news hoarding to examine how firm‐level climate risk translates into stock price crashes through investor behaviour. Using a novel text‐based measure of climate exposure extracted from earnings call transcripts, we capture firm‐specific regulatory, physical and ...
Hoa Phan, Nhan Huynh, Cuong Nguyen, Nirav Parikh, Lurion de Mello   +4 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Influence of Contact Pressure on Performance and Crossover in Zero‐Gap Alkaline Water Electrolysis

Chemie Ingenieur Technik, EarlyView.
Cell performance and product gas quality in zero‐gap alkaline water electrolysis are influenced by the mechanical contact pressure in the electrode area. With a newly developed contact‐pressure cell, it was found that the influence of contact pressure can vary drastically, depending on the cell configuration, electrode type, and diaphragm.
Lukas Ritz, Johanna Güttler, Eugen Hoppe, Martin Müller, Anna K. Mechler, Felix Lohmann‐Richters   +5 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Electrical resistance tomography for process intensification of gas–liquid stirred tanks: A comparison of linear back projection and sensitivity conjugate gradient algorithms

The Canadian Journal of Chemical Engineering, EarlyView.
Monitoring gas–liquid dynamics using Electrical resistance tomography for process intensification in stirred tanks Abstract Electrical resistance tomography (ERT) is a non‐invasive technique widely applied to the study of multiphase flows, where phases exhibit different electrical properties.
Federico Alberini, Giuseppina Montante, Alessandro Paglianti   +2 more
wiley   +1 more source

p.M918W, a novel RET germline variant: a case report and literature review of the possible association of multiple endocrine neoplasia type 2B and Charcot-Marie-Tooth disease

Endocrine Journal
Multiple endocrine neoplasia type 2B (MEN2B) is a rare autosomal dominant disorder caused by germline pathogenic RET variants. On the other hand, Charcot–Marie–Tooth disease (CMT) is a hereditary neurological disorder, characterized by distal muscle ...
Mami Sato, Rei Kubota, Shinya Uchino, Takayuki Morita, Ryoyu Niikuni, Teruhisa Udagawa, Yoshiya Hagiwara, Miyako Tanaka, Miku Sato, Yuta Tezuka, Kei Omata, Yoshikiyo Ono, Kazuhiro Haginoya, Noriaki Nakashima, Keisei Fujimori, Takanori Ishida   +15 more
doaj   +1 more source

THE MAIN DECISIONS OF HEADS OF STATE AND GOVERNMENT IN NORTH ATLANTIC COUNCIL MEETING, ON SEPTEMBER 2014 [PDF]

Annals: Series on Military Sciences, 2014
The paper is generous and full of political and security significances and also represents an issue of high interest, given the latest developments in the Euroatlantic Area in general, and in the wider Black Sea area in particular.
Eugen SITEANU, Benone ANDRONIC
doaj  

Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers

The Canadian Journal of Chemical Engineering, EarlyView.
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger, Sálvio Lima de Carvalho Neto, Silvio Edegar Weschenfelder, Glaucia Rodrigues Vieira de Almeida da Fonseca, Maria de Fátima Rodrigues da Cunha, Selene Maria Arruda Guelli Ulson de Souza, Evandro Balestrin, Adriano da Silva   +7 more
wiley   +1 more source

A post-irradiation-induced replication stress promotes RET proto-oncogene breakage

European Thyroid Journal
Objective: Ionizing radiation generates genomic instability by promoting the accumulation of chromosomal rearrangements. The oncogenic translocation RET/PTC1 is present in more than 70% of radiation-induced thyroid cancers.
Fabio Hecht, Laura Valerio, Carlos Frederico Lima Gonçalves, Marylin Harinquet, Rabii Ameziane El Hassani, Denise P Carvalho, Stephane Koundrioukoff, Jean-Charles Cadoret, Corinne Dupuy   +8 more
doaj   +1 more source

OPINIONS ABOUT MILITARY LOGISTICS IN A TURBULENT MEDIUM SECURITY [PDF]

Annals: Series on Military Sciences, 2013
In the natural world, turbulence involves violent demonstrations, random appearances, unpredictability. Scientists have developed chaos theory to explain some possible variants of development of events that have a given initial state and a number of ...
Mircea UDRESCU, Eugen SITEANU
doaj