Results 11 to 20 of about 60,412 (260)
Disease Models & Mechanisms, 2022 RET is a receptor tyrosine kinase with oncogenic potential in the mammary epithelium. Several receptors with oncogenic activity in the breast are known to participate in specific developmental stages.
Sabrina A. Vallone +8 more
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Current status of the prognostic molecular markers in medullary thyroid carcinoma
Endocrine Connections, 2020 Medullary thyroid cancer (MTC) is a rare thyroid malignancy, which arises from parafollicular C-cells. It occurs in the hereditary or sporadic form. Hereditary type is a consequence of activation of the RET proto-oncogene by germline mutations, whereas ...
Malgorzata Oczko-Wojciechowska +4 more
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Non-small-cell lung cancer: how to manage RET-positive disease
Drugs in Context, 2022 Targeted therapy has dramatically changed the history and outcomes of oncogene-addicted non-small-cell lung cancer (NSCLC). RET rearrangements are typically observed in about 1–2% of NSCLC, resulting in constitutive activation of downstream signalling ...
Elisa Andrini +6 more
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Germline genetic variants in pheochromocytoma/paraganglioma: single-center experience
Endocrine Oncology, 2023 Pheochromocytoma and paragangliomas (PPGLs) are rare neuroendocrine tumors carrying 25–40% pathogenic germline gene variants (PGVs). We evaluated clinical, laboratory, and germline molecular profile of 115 patients with pathologic (14 patients were ...
José V Lima Jr +6 more
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Passage - Tidsskrift for litteratur og kritik, 2009 Henrik Skov Nielsen: At give ret, ret at ...
openaire +4 more sources
COMMAND AND CONTROL IN MODERN MILITARY OPERATIONS [PDF]
Annals: Series on Military Sciences, 2009 "A strong collective defense of our populations, territory and forces is the core purpose of the Alliance and remains our most important security task". A memorable sentence from the Final Declaration of the Kohl/Strasbourg Summit, in April 2009, which,
Eugen BADALAN, Florian PINTA
doaj
The Mouse That Roared: The Democratic Movement in Hong Kong [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2016 The popular uprising in recent years in Hong Kong – “Occupy Central” a.k.a. Umbrella Movement – has again brought to the fore the question of the Special Administrative Region’s relationship with Mainland China post-1997 “handover” of the territory by ...
Arif Dirlik
doaj
RET signaling pathway and RET inhibitors in human cancer
Frontiers in Oncology, 2022 Rearranged during transfection (RET) receptor tyrosine kinase was first identified over thirty years ago as a novel transforming gene. Since its discovery and subsequent pathway characterization, RET alterations have been identified in numerous cancer types and are most prevalent in thyroid carcinomas and non-small cell lung cancer (NSCLC).
Angelina T. Regua +3 more
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The frequency of mutations in advanced thyroid cancer in Japan: a single-center study
Endocrine JournalWe analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. Patients (n = 96) with unresectable or metastatic thyroid carcinoma were included for retrospective chart review.
Soji Toda +8 more
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Endocrine ConnectionsNext-generation sequencing (NGS) is of great benefit to clinical practice in terms of identifying genetic alterations. This study aims to clarify the gene background and its influence on thyroid tumors in the Chinese population.
Xu-Feng Chen +6 more
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