Results 31 to 40 of about 94,066 (297)

Revista Economia & Tecnologia (RET), Vol. 6, Nº 4 (2010)

, 2005
[Versão ...
*, RET
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ROMANIAS DEFENCE INFRASTRUCTURE DEVELOPMENT [PDF]

Annals: Series on Military Sciences, 2011
It is obvious that the infrastructure for defense represents a vital necessity for every nation in the context of the present day processes of European and international integration. Provision of current security, both at the European and national levels,
Eugen BĂDĂLAN, Eugen SITEANU
doaj  

RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells

Endocrine Connections, 2021
A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile,
Cristina Romei, Teresa Ramone, Chiara Mulè, Alessandro Prete, Virginia Cappagli, Loredana Lorusso, Liborio Torregrossa, Fulvio Basolo, Raffaele Ciampi, Rossella Elisei   +9 more
doaj   +1 more source

Deciphering the Photopolymerization‐Induced Nanostructures and Interface Formation for Submicrometer Additive Manufacturing

Advanced Functional Materials, EarlyView.
This work reveals the UV‐curing‐induced monomer‐rich domain, oligomer‐rich domain, and entangled oligomer domain. The cured submicron films in stressed state induce interlayer nano‐wrinkle structures during the deposition of the second layer. Stress‐free cured films in relaxed state form non‐diffusive, diffusive and semi‐diffusive interlayer ...
Shouzheng Chen, Yufeng Zhai, Jungui Zhou, Lixing Li, Simon Schraad, Guangjiu Pan, Xuehe Jiang, Sarathlal Koyiloth Vayalil, Rolf A. T. M. van Benthem, Julien R. G. Navarro, Johan F. G. A. Jansen, Mats K. G. Johansson, Peter Müller‐Buschbaum, Stephan V. Roth   +13 more
wiley   +1 more source

THE TOPICALITY OF RULER NEAGOE BASARAB'S MILITARY THINKING ON WAR AND ARMY [PDF]

Annals: Series on Military Sciences, 2010
Our great poet Vasile Alecsandri, making reference to the brilliant minds and epochal achievements of waivodes, rulers and past famous men of culture of the Romanian people, who served and protected in an exemplary manner our Country, Origin and ...
FIorian TUCĂ, Eugen SITEANU
doaj  

Revista Economia & Tecnologia (RET), vol. 7, Nº 3 (2011)

, 2011
[Versão ...
*, RET
core   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

Advanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti, Eva Clemente, Emanuela Mensà, Marco de Maria, Fulvia Farabegoli, Emanuela Saracino, Barbara Bortolani, Emanuela Marcelli, Renato Brandimarti, Dario de Biase, Giampaolo Zuccheri   +10 more
wiley   +1 more source

Deciphering the Role of Energy Transfer Configuration in PFAS Recognition by Metal‐Organic Frameworks

Angewandte Chemie, EarlyView.
Spatial organization of Eu/Tb centers in EuTb‐FDA MOFs is employed to regulate Tb‐to‐Eu energy transfer configuration for ratiometric PFAS sensing. Directional energy transfer amplifies PFAS‐induced optical perturbations into opposite lanthanide emission responses, with enhanced Tb emission and quenched Eu emission, thereby amplifying the sensing ...
Jiatong Huo, Zongsu Han, Zhaoyi Liu, Xincheng Liu, Joshua Rushlow, Hong‐Cai Zhou   +5 more
wiley   +2 more sources

THE PLACE AND ROLE OF MILITARY SCIENCE IN THE SCIENCE UNIVERSE [PDF]

Annals: Series on Military Sciences, 2010
In the condition of current revolution in the military field, as a result of scientific discoveries and social and economic changes Iland of the evolution of human society, the military phenomenon needs a proper scientific foundation for these changes.
Eugen BĂDĂLAN, Eugen SITEANU
doaj