Results 31 to 40 of about 60,412 (260)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
THE PLACE AND ROLE OF MILITARY SCIENCE IN THE SCIENCE UNIVERSE [PDF]
Annals: Series on Military Sciences, 2010 In the condition of current revolution in the military field, as a result of scientific discoveries and social and economic changes Iland of the evolution of human society, the military phenomenon needs a proper scientific foundation for these changes.
Eugen BĂDĂLAN, Eugen SITEANU
doaj
Biomarker testing in non-small cell lung carcinoma – More is better: A case series
Cancer Research, Statistics, and Treatment, 2020 Background: Biomarker-driven lung adenocarcinomas involving alterations in oncogenic drivers such as EGFR, ALK, ROS1, and NTRK have witnessed a dramatic shift in the therapeutic and prognostic landscape owing to the development of molecular targeted ...
Ullas Batra +6 more
doaj +1 more source
Advanced Robotics Research, EarlyView.Intelligent Sky Guardians (InSkyGuard) is introduced as a four‐drone swarm that autonomously detects, tracks, and safely captures rogue drones using a coordinated net system. Computer vision and leader–follower control architecture enable synchronized enclosure, while integrated failsafes enhance system reliability. Validated through closed‐environment
Joshua Hastings +6 more
wiley +1 more source
GREAT UNIFICATION MONUMENTS [PDF]
Annals: Series on Military Sciences, 2011 Few years after Great Romania was set up, when Nicolae Iorga participated in the unveiling of some monuments dedicated to the historic event from 1st of December 1918, he appreciated that "the monuments and memorial sites represent the vivid history of ...
Floriean TUCA, Eugen SITEANU
doaj
Advanced Science, EarlyView.This work designs a peptide‐free polyelectrolyte with stable, switchable conformations and near‐infrared fluorescence in water. It harnesses a cooperative Fe3+‐triggered sheet‐to‐helix transition to generate nonlinear fluorescence quenching, enabling the ultrasensitive, real‐time visualization of Fe3+ ion distribution and metabolic trafficking at ...
Yeqiang Zhou +9 more
wiley +1 more source
THE IMPACT OF SCIENCE AND TECHNOLOGY ON MILITARY STRATEGY [PDF]
Annals: Series on Military Sciences, 2012 In this article, some opinions regarding the between military sciences (and also technologies) and the military strategy are briefly presented. There are credible arguments that the modem and reliable technologies nave been a catalyst and a driving ...
Ion Alexandru PLĂVICIOSU +1 more
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RET kinase inhibitors for RET -altered thyroid cancers
Therapeutic Advances in Medical Oncology, 2022 Precision oncology has opened a new era in cancer treatment focused on targeting specific cellular pathways directly involved in tumorigenesis. The REarrangement during Transfection ( RET) proto-oncogene is involved in the pathogenesis of various thyroid cancer subtypes.
Danica M. Vodopivec, Mimi I. Hu
openaire +3 more sources
Advanced Science, EarlyView.Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu +9 more
wiley +1 more source
CYBERSPACE RISKS AND THREATS TO CRITICAL INFORMATION INFRASTRUCTURE [PDF]
Annals: Series on Military Sciences, 2011 Critical infrastructures are those physical and cyber-based systems essential to the minimal economy and government operations. They include but are not limited to, telecommunications, energy, banking and finance, transportation, water systems and ...
Constantin MINCU, Gruia TIMOFTE
doaj