Results 31 to 40 of about 45,498 (228)

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho   +27 more
wiley   +1 more source

Utility of reticulocyte indices in the diagnosis of pancytopenia

open access: yesJournal of Family Medicine and Primary Care, 2022
Introduction: Pancytopenia is a hematological condition in which there is a reduction in all three cell lines of blood. This study aims to evaluate the utility of reticulocyte indices such as reticulocyte % (retic %), immature reticulocyte fraction (IRF),
Jonali Das   +4 more
doaj   +1 more source

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard   +7 more
wiley   +1 more source

Value of combined monitoring of hemolytic reaction indicatorsin efficacy assessment of lymphoma-associated hemophagocytic lymphohistiocytosis secondary to Evans syndrome

open access: yesZhongguo shuxue zazhi
[Objective] To investigate the value of combined monitoring of hemolytic reaction indicators in the efficacy assessment of lymphomaassociated hemophagocytic lymphohistiocytosis (LAHLH) secondary to Evans syndrome (ES).
AO Zhengcai, WANG Hui, XU Yuxia
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Novel markers in predicting Brucella sacroiliitis: The platelet large cell ratio and basal immature reticulocyte fraction

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Objective: To present platelet large cell ratio (P-LCR), reticulocyte, and immature reticulocyte fraction (IRF) values as novel parameters in diagnosis and response to treatment in patients developing sacroiliitis.
Neslihan Celik   +2 more
doaj   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

open access: yesFood Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid   +8 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Correction of Poikylocytosis and Blood Biochemical Indicators in Acute Blood Loss

open access: yesОбщая реаниматология, 2015
Objective: to provide a rationale for the use of perfluorane to correct erythrocyte morphological changes and blood biochemical indicators in acute blood loss.Material and methods.
V. V. Moroz   +5 more
doaj   +1 more source

Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort

open access: yesBMC Endocrine Disorders, 2023
Background Obesity is associated with type 2 diabetes mellitus and chronic low-grade inflammation. Although chronic inflammatory conditions and diabetes are associated with anaemia, less is known about associations of obesity and body shape, independent ...
Sofia Christakoudi   +3 more
doaj   +1 more source

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