Results 61 to 70 of about 42,523 (238)

Reticulocytes and reticulocyte enumeration [PDF]

Journal of Clinical Laboratory Analysis, 2001
R S, Riley, J M, Ben-Ezra, R, Goel, A, Tidwell   +3 more
openaire   +2 more sources

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Fatty Acid β-Oxidation May Be Associated with the Erythropoietin Resistance Index in Stable Patients Undergoing Haemodialysis

Diagnostics
Background/Objectives: Lipid metabolism and adiponectin modulate erythropoiesis in vitro and in general population studies and may also affect responsiveness to erythropoietin in patients undergoing haemodialysis (HD).
Shuhei Kidoguchi, Kunio Torii, Toshiharu Okada, Tomoko Yamano, Nanami Iwamura, Kyoko Miyagi, Tadashi Toyama, Masayuki Iwano, Ryoichi Miyazaki, Yosuke Shigematsu, Hideki Kimura   +10 more
doaj   +1 more source

National Bleeding Disorder Foundation Clinical Practice Recommendations for Laboratory Screening of Iron Deficiency With and Without Anemia in the Inherited Bleeding Disorders Population

Haemophilia, EarlyView.
ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli, Magdalena D. Lewandowska, Ming Y. Lim, Kelly Tickle, Maureen K. Baldwin, Rose Bender, Jennifer Davila, Brendan Hayes, Amanda Jacobson‐Kelly, Peter Kouides, Michele P. Lambert, Shilpa Nataraj, Michelle Sholzberg, Roona Sinha, Hanny Al‐Samkari, Amy L. Dunn   +15 more
wiley   +1 more source

Unexplained Elevated Vitamin B12: Consider Macro‐B12

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans, Ruben Deneer, Marten R. Nijziel, Volkher Scharnhorst   +3 more
wiley   +1 more source

Prognostic value of a number of blood laboratory parameters in the use of erythropoiesis-stimulating agents in anemic patients with lymphoproliferative diseases

Терапевтический архив, 2013
AIM: To clarify the prognostic value of the baseline blood levels of endogenous erythropoietin (EE) and tumor necrosis factor-α (TNF-α) involved in the key components of the pathogenesis of anemia in lymphoproliferative diseases (LPD), the counts of ...
N A Romanenko, S S Bessmel'tsev, M V Berkos, O E Rozanova, K M Abdulkadyrov   +4 more
doaj  

Reticulocytosis in screen-printing workers exposed to 2-butoxyethanol and 2-ethoxyethanol

Annals of Occupational and Environmental Medicine, 2017
Background Studies on the hematologic toxicity of ethylene glycol ethers in humans are limited. Therefore, the aim of this study was to examine the association between exposure to solvents (containing 2-butoxyethanol and 2-ethoxyethanol) and ...
Seng-Ho Song, Seong-Kyu Kang, Won-Jun Choi, Kyeong Min Kwak, Dong-Hoon Lee, Dyuk-Yoon Kang, Sang-Ha Lee   +6 more
doaj   +1 more source

Lipoxygenase mRNA in cultured human epidermal and oral keratinocytes

Journal of Lipid Research, 1995
Although 15-lipoxygenase has not been purified from cultured human keratinocytes nor has cDNA coding for the protein been isolated from this source, this enzyme activity is implied by the finding of its stereospecific product in in vitro experiments ...
H Zhao, B Richards-Smith, A N Baer, F A Green   +3 more
doaj   +1 more source

The effect of perioperative erythropoietin‐stimulating agents and intravenous iron on patient outcomes following solid organ transplantation: A systematic review

Transfusion Medicine, EarlyView.
Abstract Solid organ transplant is associated with high rates of anaemia and transfusion, but there is little comparative data on interventions such as erythropoietin‐stimulating agents (ESAs) and intravenous (IV) iron. We conducted a systematic review examining the association of ESAs and IV iron with outcomes in adults undergoing solid organ ...
Frank Lee, Quentin Eichbaum, Christine Cserti‐Gazdewich, Darren Mullane, Frederick W. Lombard, Jeremy W. Jacobs, Katerina Pavenski, Marina Englesakis, Alexander Dotto, Terry Cho, Andrés Leonard‐Reixa, Jacqueline Trudeau, Andrew W. Shih, Justyna Bartoszko   +13 more
wiley   +1 more source