Results 91 to 100 of about 26,590 (287)
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij +11 more
wiley +1 more source
Reticulocyte counts in the aged.
Reticulocytes were measured on an automated reticulocyte counter in five groups; healthy adults, non-elderly patient with low hematopoiesis, adults with anemia, healthy elderly persons and elderly patients with anemia. The reticulocyte percent, absolute reticulocyte count, and reticulocyte composition as classified by fluorescence intensity (highly ...
Kojima, Kazuhide, Tatsumi, Noriyuki
openaire +3 more sources
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear +6 more
wiley +1 more source
Pharmacologic Inhibition of Erythrocyte Ferroportin Expression Exacerbates Plasmodium Infection
Plasmodium parasites rely on host iron for survival and replication, making host iron availability a critical determinant of malaria pathogenesis. Central to iron homeostasis is the hepcidin–ferroportin regulatory axis, where hepcidin suppresses iron ...
Sareh Zeydabadinejad +6 more
doaj +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source
A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM [PDF]
Context: The recombinant human erythropoietin (rHuEPO) stimulates the erythropoiesis process. Because this glycoprotein has a short half-life, it needs to be administrated two to three times a week.
Gledys Reynaldo +12 more
doaj
Background: Reticulocytes are immature red blood cells containing RNA remnants. Their population kinetics has been documented under various in vivo and in vitro conditions, including after storage of red blood cells in blood banks.
Adriana Urbina, Fernando Palomino
doaj +1 more source
The maturation of reticulocytes. I. Following introduction of reticulocytes into polycythemic and normocythemic animals [PDF]
Investigations were conducted on the life-span of "stress" reticulocytes and the fate of the early denucleated large-sized reticulocytes in circulating blood.
Shimada, Atsuko
core
IFN-γ plays both pathological and protective roles during blood-stage malaria. One of its pathological roles is its contribution to anemia by suppressing erythropoiesis. Here, to evaluate the effects of IFN-γ-mediated alterations in erythropoiesis on the
Hiroko eOkada +7 more
doaj +1 more source
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao +8 more
wiley +1 more source

