Results 111 to 120 of about 22,655 (235)
ABSTRACT Introduction We investigated the stability and accuracy of platelets with MgSO4 and compared the results of blood counts between MgSO4 and K2EDTA. Methods Platelet stability as a function of time was assessed on the XN Sysmex analyzer by comparing the percentage deviation to the desirable bias of the EFLM.
Michel Soulard +4 more
wiley +1 more source
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang +9 more
wiley +1 more source
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang +18 more
wiley +1 more source
Single-cell transcriptomics reveals heterocellular γ-globin gene expression in Aγδβ-thalassemia. [PDF]
Doerfler PA +13 more
europepmc +1 more source
One cell at a time: HbF distribution in sickle cell disease. [PDF]
Khandros E, Steinberg MH.
europepmc +1 more source
ABSTRACT Lead poisoning should be considered in patients presenting with unexplained anemia and abdominal pain, even without clear environmental or occupational exposure. Recognizing classic signs such as Burton's line and basophilic stippling enables timely diagnosis and effective chelation therapy.
Jennifer Eichler +2 more
wiley +1 more source
Luspatercept ameliorates disease phenotype and complications in the Townes mouse model of sickle cell disease. [PDF]
Sezaki M +7 more
europepmc +1 more source
From Hemolysis to Lupus: A Case of Evans Syndrome Revealing Systemic Autoimmunity
ABSTRACT Evans syndrome (ES), the coexistence of autoimmune hemolytic anemia and immune thrombocytopenia, can unmask systemic autoimmune disease. We report a 30‐year‐old woman who presented with fatigue, jaundice, pallor, and mucocutaneous bleeding.
Biruk T. Mengistie +6 more
wiley +1 more source
Luspatercept for the treatment of transfusion-dependent non-severe aplastic anemia. [PDF]
Jia X +7 more
europepmc +1 more source

