Results 41 to 50 of about 39,677 (234)

Cone synapses in mammalian retinal rod bipolar cells [PDF]

open access: yesJournal of Comparative Neurology, 2018
AbstractSome mammalian rod bipolar cells (RBCs) can receive excitatory chemical synaptic inputs from both rods and cones (DBCR2), but anatomical evidence for mammalian cone‐RBC contacts has been sparse. We examined anatomical cone‐RBC contacts using neurobiotin (NB) to visualize individual mouse cones and standard immuno‐markers to identify RBCs, cone ...
Ji‐Jie Pang   +3 more
openaire   +2 more sources

Temporal order of bipolar cell genesis in the neural retina

open access: yesNeural Development, 2008
Background Retinal bipolar cells comprise a diverse group of neurons. Cone bipolar cells and rod bipolar cells are so named for their connections with cone and rod photoreceptors, respectively.
Chen C-M Amy   +2 more
doaj   +1 more source

A Promising Combination: PACAP and PARP Inhibitor Have Therapeutic Potential in Models of Diabetic and Hypertensive Retinopathies

open access: yesCells, 2021
Diabetes and hypertension are complex pathologies with increasing prevalence nowadays. Their interconnected pathways are frequently manifested in retinopathies.
Etelka Pöstyéni   +3 more
doaj   +1 more source

A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Inherited retinal dystrophies (IRDs) are characterized by progressive degeneration and loss of light-sensing photoreceptors. The most promising therapeutic approach for IRDs is gene supplementation therapy using viral vectors, which requires the presence
Elisa Murenu   +12 more
doaj   +1 more source

Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells. [PDF]

open access: yesPLoS ONE, 2014
Nitric oxide (NO) is involved in retinal signal processing, but its cellular actions are only partly understood. An established source of retinal NO are NOACs, a group of nNOS-expressing amacrine cells which signal onto bipolar, other amacrine and ...
Alex H Vielma   +4 more
doaj   +1 more source

Labelling and targeted ablation of specific bipolar cell types in the zebrafish retina

open access: yesBMC Neuroscience, 2009
Background Development of a functional retina depends on regulated differentiation of several types of neurons and generation of a highly complex network between the different types of neurons.
Ellingsen Staale   +2 more
doaj   +1 more source

Long-term rearrangement of retinal structures in a novel mutation of X-linked retinoschisis [PDF]

open access: yes, 2017
The aim of the present study was to report a novel mutation in the retinoschisin 1 (RS1) gene in a Caucasian family affected by X-linked juvenile retinoschisis (XLRS) and to describe the long-term modification of retinal structure.
Colavito, Davide   +7 more
core   +1 more source

A Novel In Vitro Sensing Configuration for Retinal Physiology Analysis of a Sub-Retinal Prosthesis

open access: yesSensors, 2012
This paper presents a novel sensing configuration for retinal physiology analysis, using two microelectrode arrays (MEAs). In order to investigate an optimized stimulation protocol for a sub-retinal prosthesis, retinal photoreceptor cells are stimulated,
Kyung Hwan Kim   +6 more
doaj   +1 more source

An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model

open access: yesScientific Reports, 2023
Retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are characterized by unrelenting neuronal death. However, electrical stimulation has been shown to induce neuroprotective changes in the retina capable of ...
Alejandra Gonzalez Calle   +9 more
doaj   +1 more source

Amacrine cells differentially balance zebrafish color circuits in the central and peripheral retina

open access: yesCell Reports, 2023
Summary: The vertebrate inner retina is driven by photoreceptors whose outputs are already pre-processed; in zebrafish, outer retinal circuits split “color” from “grayscale” information across four cone-photoreceptor types.
Xinwei Wang   +4 more
doaj   +1 more source

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