Results 51 to 60 of about 39,677 (234)
Cell Reports, 2020 Summary: Otx family homeoproteins Otx2 and Crx are expressed in photoreceptor precursor cells and bind to the common DNA-binding consensus sequence, but these two proteins have distinct functions in retinal development.
Haruka Yamamoto +3 more
doaj +1 more source
Membrane currents in retinal bipolar cells of the axolotl. [PDF]
The Journal of general physiology, 1988 By whole-cell patch-clamping bipolar cells isolated from enzymatically dissociated retinae, we have studied the nonsynaptic ionic currents that may play a role in shaping the bipolar cell light response and in determining the level of voltage noise in these cells.
M, Tessier-Lavigne +3 more
openaire +2 more sources
The AII Amacrine Cell Connectome: A Dense Network Hub
Frontiers in Neural Circuits, 2014 The mammalian AII retinal amacrine cell is a narrow-field, multistratified glycinergic neuron best known for its role in collecting scotopic signals from rod bipolar cells and distributing them to ON and OFF cone pathways in a crossover network via a ...
Robert E Marc +4 more
doaj +1 more source
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong +5 more
core +2 more sources
Continuous Vesicle Cycling in the Synaptic Terminal of Retinal Bipolar Cells [PDF]
Neuron, 1996 Endocytosis and exocytosis were investigated in the synaptic terminal of retinal bipolar cells by monitoring the uptake and loss of the fluorescent dye FM1-43. Depolarization in the presence of Ca2+ stimulated a continuous cycle of exocytosis and endocytosis that was approximately balanced at rates up to 3800 vesicles per s.
Lagnado, Leon, Gomis, Ana, Job, Christy
openaire +3 more sources
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. [PDF]
, 2020 Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that ...
Benavente, Claudia A +8 more
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Negative modulation of the GABAAρ1 receptor function by l-cysteine [PDF]
, 2017 l-Cysteine is an endogenous sulfur-containing amino acid with multiple and varied roles in the central nervous system, including neuroprotection and the maintenance of the redox balance.
Beltrán González, Andrea Natalia +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
PLoS ONE, 2012 Irx7, a member in the zebrafish iroquois transcription factor (TF) family, has been shown to control brain patterning. During retinal development, irx7's expression was found to appear exclusively in the inner nuclear layer (INL) as soon as the ...
Yuqing Zhang +4 more
doaj +1 more source
Untersuchung zur Expression und Funktion von HCN-Kanälen in Photorezeptoren und Bipolarzellen der Mäuseretina [PDF]
, 2005 The aim of this study was to examine the expression and the functional properties of HCN- channels (hyperpolarization-activated and cyclic nucleotide-gated) in photoreceptors and bipolar cells of the mouse retina.
Thiel, Frank
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